Results 41 to 50 of about 490,102 (254)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Safety concerns with salmeterol [PDF]
The introduction of long-acting beta2 agonists, such as salmeterol and eformoterol, has been an important development...
openaire +1 more source
Though socially anxious individuals tend to seek safety, little is known about whether this relationship depends on context, including the affordances of social networking sites (SNSs) to provide anonymity and publicness, and whether safety-seeking can ...
Xue-Qin Yin +4 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Development of the nuclear safety trust indicator
This study went beyond making an indicator simply based on theoretical arguments, and explored a wide spectrum of different types of perceptions about energy safety to make a concept of energy safety for the Korean society.
SeongKyung Cho
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
MODERN ARCHITECTONICS OF STUDYING THE CATEGORY OF ECONOMIC SAFETY
Different approaches to defining the term of “economic safety” are analyzed in the paper. Structural units of this term are determined. The author suggests her own point of view on this term.
I. M. Glotina
doaj
The purpose of this study was to discover if a relationship existed between the most common safety concerns and the most common UAS accidents with regards to the integration of military unmanned aerial systems (UAS) into the National Airspace System (NAS)
Omar J Hamilton +2 more
doaj +1 more source

