Results 81 to 90 of about 1,174,768 (293)

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Assessment of driver compliance on roadside safety signs with auditory warning sounds generated from pavement surface–a driving simulator study

open access: yesJournal of Traffic and Transportation Engineering (English ed. Online), 2018
A variety of word messages are used in highways in different forms to inform drivers of traffic safety information or to influence positively drivers' behavior.
Min-Wook Kang, Salah Uddin Momtaz
doaj   +1 more source

TiEV: The Tongji Intelligent Electric Vehicle in the Intelligent Vehicle Future Challenge of China

open access: yes, 2018
TiEV is an autonomous driving platform implemented by Tongji University of China. The vehicle is drive-by-wire and is fully powered by electricity. We devised the software system of TiEV from scratch, which is capable of driving the vehicle autonomously ...
Cai, Lewen   +18 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

The influence of driving safety attitudes on risky driving behavior: a driving simulator study

open access: yesЭкстремальная психология и безопасность личности
Context and relevance. Road traffic accidents and violations of traffic regulations continue to be a frequent occurrence on highways, particularly among motor vehicle operators who demonstrate a tendency to disregard fundamental driving safety
M. Chrisnatalia   +4 more
doaj   +1 more source

Research on Safety and Static-Dynamic Legibility of Distressed Pavement

open access: yesDiscrete Dynamics in Nature and Society, 2015
In order to study the impacts of distressed pavement on driving safety, the drivers’ driving behavior and driving characteristics need to be analyzed. By analyzing the drivers’ characteristics, driving behavior’ and braking characteristics of vehicles ...
Chengyuan Mao   +3 more
doaj   +1 more source

Methodology to assess safety effects of future Intelligent Transport Systems on railway level crossings [PDF]

open access: yes, 2012
There is consistent evidence showing that driver behaviour contributes to crashes and near miss incidents at railway level crossings (RLXs). The development of emerging Vehicle-to-Vehicle and Vehicle-to-Infrastructure technologies is a highly promising ...
Haworth, Narelle   +2 more
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

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