Results 111 to 120 of about 7,677,659 (304)
Development of Statutory Methods for Calculation and Design of Tribo-Fatigue Systems. Part 1
The article discusses briefly the principles that can be used as a basis for the development of normative methods for the calculation and design of Tribo-Fatigue systems.
Oleg M. Yelovoy +1 more
doaj
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Independence-Monmouth Traffic Safety Management Program (TSMP)
Cover letter title: Independence-Monmouth Traffic Safety Management Program (TSMP).At head of title: Preliminary."July 1981.""OTSC Project #81-02-5-609."This archived document is maintained by the State Library of Oregon as part of the Oregon Documents ...
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Effect of terahertz irradiation on DNA damage repair in living cells
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
Oregon traffic safety performance plan. Annual report
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Fiscal year 1998-Vols.
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System Safety Bookshelf: Applying Safety Standards to Life-Saving Equipment
Elsevier Academic Press has recently published a new safety book titled Safety Risk Management for Medical Devices, written by Bijan Elahi. This book explains how to conduct a risk management program that will show conformance to the FDA safety standards
Ericson, Clif, Clif Ericson
core +1 more source
Strength and Deformation of Pillars during Mining in the Shaft Pillar
This study of the strength and deformation of coal samples was triggered by the need to define the stress–strain characteristics of pillars during room and pillar mining in the shaft protective pillar at the ČSM Mine.
Jindřich Šancer +3 more
doaj +1 more source
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source

