Results 31 to 40 of about 1,182,306 (304)

Measuring resilient safety culture of construction projects

, 2019
Resilient safety culture is characterised by continuous improvements of safety performance and the capability of creating foresight, recognising and anticipating the changing shape of safety risks in the complex sociotechnical systems. This study aims to
Feng, Yingbin (R16766), Trinh Minh, Tri (S32678)   +1 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Experimental investigation into the Impact of Cyclic High Low Pressure Water Immersion on the Pore structure and Mechanical properties of coal

Scientific Reports
The extraction of coal seams with high gas content and low permeability presents significant challenges, particularly due to the extended period required for gas extraction to meet safety standards and the inherently low extraction efficiency.
Pi Zikun, Li Rui, Wang Yan, Xiong Jiawen, Li Jiayi, Zhang Yifu, Peng Bin   +6 more
doaj   +1 more source

A new digital surface crack image monitoring technology for coal failure

Energy Science & Engineering, 2023
The experimental study on the variation law of coal fracture and stress was carried out in the laboratory and engineering fields, respectively. A multiparameter monitoring system including electromagnetic radiation and a high‐speed camera was built, and ...
Yankui Li, Xiaoguang Qiao, Baisheng Nie, Shiyue Wu, Tao Zhao, Yuxi Huang, Xinghua Zhang   +6 more
doaj   +1 more source

Understanding the role of local safety groups in managing safety practices between micro construction firms and principal contractors [PDF]

, 2014
Construction projects incorporate the input of a range of tradesmen and different sized firms, ranging from micro to large organisations. Working practices of micro construction firms are carried out in an informal manner while larger organisations tend ...
Aboagye-Nimo, Emmanuel; id_orcid, Aboagye-Nimo, E, Raiden, Ani, Raidén, A, King, A, King, Andrew   +5 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Evolution law of overlying rock fracture field in goaf mining with double-roof-cutting retaining roadway

Scientific Reports
This study comprehensively combines physical analog modeling, numerical simulation, on-site monitoring, and other methods to explore the overburden rock fissure development characteristics under double-roof-cutting (DRC) with retained roadway conditions.
Xiaobo Lv, Shengyong Hu, Jun Nian, Chunsheng Deng, Bo Zhao, Cheng He, Yansheng Wang, Xitu Zhang, Wei Zhang   +8 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Gas migration control in goaf with double roof cutting and retaining roadway

Scientific Reports
The behavior of gas migration in goaf under double roof cutting conditions directly influences the effectiveness of gas control measures. This study employs a combination of numerical simulation and field verification to investigate the patterns of gas ...
Xiaobo Lv, Shengyong Hu, Jun Nian, Chunsheng Deng, Bo Zhao, Cheng He, Yansheng Wang, Xitu Zhang, Wei Zhang   +8 more
doaj   +1 more source