Results 41 to 50 of about 11,989,757 (288)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Study on the influence of forced ventilation on the maximum fire temperature in roadway heading

Scientific Reports
This study investigates the maximum temperature in tunnel fires under forced ventilation conditions by constructing a 1:10 scale experimental model and using numerical simulations. A dimensionless derivation of the maximum temperature is provided for the
Bolun Li, Yucheng Li, Yinghao Sun, Wei Zhang, Junqiao Li, Zhitao Zhang, Yunan Cui, Jinyang Dong, Hongwei Liu   +8 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Dynamic Mechanical Properties of Sandstone Weaken Under Multiple Impacts Based on SHPB Experiments

Geofluids
Due to multiple dynamic disturbances caused by mining activities, the internal fractures in the surrounding rock of the roadway continue to expand, resulting in the continuous weakening of the mechanical properties of the sandstone.
He Yongliang, Wang Yifan, Li Chuantian, Fu Yuping   +3 more
doaj   +1 more source

A new digital surface crack image monitoring technology for coal failure

Energy Science & Engineering, 2023
The experimental study on the variation law of coal fracture and stress was carried out in the laboratory and engineering fields, respectively. A multiparameter monitoring system including electromagnetic radiation and a high‐speed camera was built, and ...
Yankui Li, Xiaoguang Qiao, Baisheng Nie, Shiyue Wu, Tao Zhao, Yuxi Huang, Xinghua Zhang   +6 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

System Safety Bookshelf: Applying Safety Standards to Life-Saving Equipment

, 2019
Elsevier Academic Press has recently published a new safety book titled Safety Risk Management for Medical Devices, written by Bijan Elahi. This book explains how to conduct a risk management program that will show conformance to the FDA safety standards
Ericson, Clif, Clif Ericson
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

A critical analysis of airline safety management with reference to pilots and aviation authority officers [PDF]

, 1996
When we consider regional differences in air safety, a call for regional solutions is needed. This research probes the current situation in Taiwan and part of Asia from a regional perspective, aiming to better understand safety management in this ...
Ho, Li-Chi
core   +4 more sources

Implementation of food safety management systems in the UK [PDF]

, 2011
This paper reports the first stage of work being undertaken to understand the factors that have impacted on the current state of food safety in the UK food manufacturing sector.
Lena Dzifa Mensah, Julien, Denyse, Denyse Julien, Mensah, Lena Dzifa   +3 more
core   +1 more source