Results 41 to 50 of about 1,182,306 (304)

A simulation experiment study to examine the effects of noise on miners’ safety behavior in underground coal mines

BMC Public Health, 2021
Background Noise pollution in coal mines is of great concern. Personal injuries directly or indirectly related to noise occur from time to time. Its effects impact the health and safety of coal mine workers.
Jing Li, Yaru Qin, Lei Yang, Zhen Wang, Ke Han, Cheng Guan   +5 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Study on the influence of forced ventilation on the maximum fire temperature in roadway heading

Scientific Reports
This study investigates the maximum temperature in tunnel fires under forced ventilation conditions by constructing a 1:10 scale experimental model and using numerical simulations. A dimensionless derivation of the maximum temperature is provided for the
Bolun Li, Yucheng Li, Yinghao Sun, Wei Zhang, Junqiao Li, Zhitao Zhang, Yunan Cui, Jinyang Dong, Hongwei Liu   +8 more
doaj   +1 more source

Assessing and developing safety management competences

, 2018
Introduction: Assessing and developing managers’ safety competence is one method for achieving high safety performance in the organisations. Objectives: The aim of this study is to construct a safety management competence development framework to help ...
S. Tappura, Tappura, Sari, J. Kivistö-Rahnasto, Kivistö-Rahnasto, Jouni   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Dynamic Mechanical Properties of Sandstone Weaken Under Multiple Impacts Based on SHPB Experiments

Geofluids
Due to multiple dynamic disturbances caused by mining activities, the internal fractures in the surrounding rock of the roadway continue to expand, resulting in the continuous weakening of the mechanical properties of the sandstone.
He Yongliang, Wang Yifan, Li Chuantian, Fu Yuping   +3 more
doaj   +1 more source

The Relationship Between Organizational Safety Culture and Organization Safety Performance. The Mediating Role of Safety Management System

, 2021
Introduction: Safety performance is defined as efforts undertaken by organizations with the crucial aim of curtailing accidents and injuries to workers. It plays a crucial role in an organization aiming to achieve an anticipated outcome.
Abd Aziz, Fadzli Shah, Omer, Faris, Otitolaiye, Victor Olabode, Munauwar, Munawar   +3 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Research on multi-parameter inversion of the phenomenon of gob breathing induced by atmospheric pressure fluctuation

Energy Exploration & Exploitation, 2022
It is significant to predict the gas emission in the mine gob accurately for gas drainage to prevent accidents and ensure safe production. The change of atmospheric pressure makes the gas emission in the mine gob presents a “breathing phenomenon”, which ...
Bing Wu, Binbin He, Chenguang Zhao, Baiwei Lei   +3 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source