Results 41 to 50 of about 3,157,380 (360)

A commentary on recent water safety initiatives in the context of water utility risk management. [PDF]

open access: yes, 2006
Over the last decade, suppliers of drinking water have recognised the limitations of relying solely on end-product monitoring to ensure safe water quality and have sought to reinforce their approach by adopting preventative strategies where risks are ...
Gale, Paul   +2 more
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

A simulation experiment study to examine the effects of noise on miners’ safety behavior in underground coal mines

open access: yesBMC Public Health, 2021
Background Noise pollution in coal mines is of great concern. Personal injuries directly or indirectly related to noise occur from time to time. Its effects impact the health and safety of coal mine workers.
Jing Li   +5 more
doaj   +1 more source

Developments in the Safety Science Domain and in Safety Management From the 1970s Till the 1979 Near Disaster at Three Mile Island [PDF]

open access: yes, 2015
Objective: What has been the influence of general management schools and safety research into causes of accidents and disasters on managing safety from 1970 till 1979?
Groeneweg, Jop   +4 more
core  

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

open access: yesFEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

The Influence of Team Human Capital on Safety Performance of Engineering Project Team: The Mediating Role of Safety Citizenship Behavior

open access: yesIEEE Access, 2021
With the further deepening and expansion of the “Belt and Road” initiative, the number and scale of various engineering project teams in China are continuously expanding, together with the associated security risks.
Zenghai Wu, Beijie Yin, Pianpian Ning
doaj   +1 more source

Decisions in safety management

open access: yesScientific Journal of the Military University of Land Forces, 2020
The article emphasizes that safety is the most important value for every person. Today, in the face of many threats, its level and interpretation are changing. The conditions of some phenomena also generate premises and possibilities for situations threatening health, life, environment, or infrastructure of a specific area to occur.
openaire   +3 more sources

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

open access: yesFEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang   +6 more
wiley   +1 more source

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