Results 71 to 80 of about 20,641,169 (265)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

An investigation of wall temperature characteristics to evaluate thermal fatigue at a T-junction pipe

open access: yesMechanical Engineering Journal, 2014
Thermal fatigue cracking may initiate at a T-junction pipe where high and low temperature fluids mix. In this study, wall temperature characteristics at a T-junction pipe were investigated to improve the evaluation method for thermal fatigue.
Koji MIYOSHI   +3 more
doaj   +1 more source

Analytical Threshold for Chaos of Piecewise Duffing Oscillator with Time-Delayed Displacement Feedback

open access: yesShock and Vibration, 2022
In this paper, the bifurcation and chaotic motion of a piecewise Duffing oscillator with delayed displacement feedback under harmonic excitation are studied.
Zhang Ming-Xin   +3 more
doaj   +1 more source

Developing System Safety Engineers for the Future: 34th International System Safety Conference

open access: yes, 2016
The 2016 ISSC took place in Orlando, Florida where, in addition to tutorials, roundtables and paper presentations (see page 45), those in attendance networked with their fellow professionals from around the world to share their ideas, find solutions to ...
Muniak, Charles
core   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

System Safety in Healthcare: White House Wants System Engineering for Safety and Reliability in Health Care

open access: yes, 2016
System safety engineering will be a great tool for designing health care systems for patient safety, but the White House has a wider goal — one that includes not only patient safety, but also reliability, efficiency, productivity, quality and cost ...
Raheja, Dev
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Safety of machinery—Supportive Protective System (SPS) (Part 1: Risk reduction of the SPS in an Integrated Manufacturing System (IMS))

open access: yesNihon Kikai Gakkai ronbunshu, 2018
Based on the worldwide situation, it is necessary for the Japanese mechanical industry to consider risk-reduction strategies that match real production site.
Shoken SHIMIZU   +6 more
doaj   +1 more source

An Innovative Method to Hypothesis Testing for System Safety Assessment [PDF]

open access: yes, 2015
The way forward in system safety engineering will be quantitative, and this paper proposes an innovative method for generating a uniform way to understand the composite of testing and experience.
Thomas, Robert   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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