Results 21 to 30 of about 456,620 (259)

Molecular estimation of neurodegeneration pseudotime in older brains

Nature Communications, 2020
The limited understanding of the temporal molecular changes in late-onset Alzheimer’s disease hinder the development of therapeutic treatment. The authors use manifold learning to develop a molecular model for disease progression from RNASeq data from ...
Sumit Mukherjee, Laura Heath, Christoph Preuss, Suman Jayadev, Gwenn A. Garden, Anna K. Greenwood, Solveig K. Sieberts, Philip L. De Jager, Nilüfer Ertekin-Taner, Gregory W. Carter, Lara M. Mangravite, Benjamin A. Logsdon   +11 more
doaj   +1 more source

Detailed characterizations of the new Mines Douai comparative reactivity method instrument via laboratory experiments and modeling [PDF]

Atmospheric Measurement Techniques, 2015
The hydroxyl (OH) radical is an important oxidant in the troposphere, which controls the lifetime of most air quality- and climate-related trace gases. However, there are still uncertainties concerning its atmospheric budget, and integrated measurements ...
V. Michoud, R. F. Hansen, N. Locoge, P. S. Stevens, S. Dusanter   +4 more
doaj   +1 more source

Author Correction: Molecular estimation of neurodegeneration pseudotime in older brains

Nature Communications, 2020
A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20261 ...
Sumit Mukherjee, Laura Heath, Christoph Preuss, Suman Jayadev, Gwenn A. Garden, Anna K. Greenwood, Solveig K. Sieberts, Philip L. De Jager, Nilüfer Ertekin-Taner, Gregory W. Carter, Lara M. Mangravite, Benjamin A. Logsdon   +11 more
doaj   +1 more source

Estimates of hospitalization attributable to influenza and RSV in the US during 1997–2009, by age and risk status

BMC Public Health, 2017
Background Estimates of influenza and respiratory syncytial virus (RSV) burden must be periodically updated to inform public health strategies. We estimated seasonal influenza- and RSV-attributable hospitalizations in the US from 1997 to 2009 according ...
Gonçalo Matias, Robert Taylor, François Haguinet, Cynthia Schuck-Paim, Roger Lustig, Vivek Shinde   +5 more
doaj   +1 more source

Humanistic and economic burden associated with depression in the United States: a cross-sectional survey analysis

BMC Psychiatry, 2022
Background Depression (major depressive disorder [MDD]) affects the functioning of patients in many facets of life. Very few large-scale studies to date have compared health and economic related outcomes of those with versus without depression, and ...
Saundra Jain, Shaloo Gupta, Vicky W. Li, Ellison Suthoff, Alix Arnaud   +4 more
doaj   +1 more source

Modelling estimates of age-specific influenza-related hospitalisation and mortality in the United Kingdom

BMC Public Health, 2016
Background Influenza is rarely confirmed with laboratory testing and accurate assessment of the overall burden of influenza is difficult. We used statistical modelling methods to generate updated, granular estimates of the number/rate of influenza ...
Gonçalo Matias, Robert J. Taylor, François Haguinet, Cynthia Schuck-Paim, Roger L. Lustig, Douglas M. Fleming   +5 more
doaj   +1 more source

Developing pathways for community-led research with big data: a content analysis of stakeholder interviews

Health Research Policy and Systems, 2020
Background Big data (BD) informs nearly every aspect of our lives and, in health research, is the foundation for basic discovery and its tailored translation into healthcare.
Shira Grayson, Megan Doerr, Joon-Ho Yu
doaj   +1 more source

Antagonist Temperature Variation Affects the Photosynthetic Parameters and Secondary Metabolites of Ocimum basilicum L. and Salvia officinalis L.

Plants, 2022
Climate change is one of the main challenges for actual and future generations. Global warming affects plants and animals and is responsible for considerable crop loss.
Lucian Copolovici, Dana M. Copolovici, Cristian Moisa, Andreea Lupitu   +3 more
doaj   +1 more source

Effect of composition on the high rate dynamic behaviour of tungsten heavy alloys

EPJ Web of Conferences, 2015
Tungsten heavy alloys are currently used as kinetic energy penetrators in military applications due to their high density and superior mechanical properties.
Latif Kesemen, Kaan Çalışkan N., Emrah Konokman H., Nuri Durlu   +3 more
doaj   +1 more source

Investigation of the Effects of the Explant Type and Different Plant Growth Regulators on Micropropagation of Five Mediterranean Salvia spp. Native to Greece

Horticulturae, 2023
Sages are medicinal and aromatic plants that constitute a large pool from which active compounds of great pharmaceutical potential can be derived, while at the same time, they also have ornamental value.
Maria Papafotiou, Georgia Vlachou, Aikaterini N. Martini   +2 more
doaj   +1 more source