Results 11 to 20 of about 1,757 (156)

Children’s tolerance of word-form variation [PDF]

Child Development Research, Volume 2012, Issue 1, 2012., 2012
How much morphological variation can children tolerate when identifying familiar words? This is an important question in the context of the acquisition of richly inflected languages where identical word forms occur far less frequently than in English. To
Alfieri, Louis, Brooks, Patricia J., Bruening, Paul R., Dabašinskienė, Ineta, Kempe, Vera   +4 more
core   +6 more sources

Identification of Ifitm1 as a Pivotal Gene in Mouse Spinal Cord Injury Using Comprehensive Machine Learning Algorithms. [PDF]

Mediators Inflamm
Background: Spinal cord injury (SCI) functions as a medical condition leading to substantial motor and neurological system deteriorations. Researchers must understand the molecular mechanisms of this disease because it serves as a foundation for creating therapeutic solutions.
Yao Y, Xi K, Xu S, Zhang F, Chen L.
europepmc   +2 more sources

Comprehensive analysis of the value of angiogenesis and stemness-related genes in the prognosis and immunotherapy of ovarian cancer. [PDF]

Biofactors
Tumor angiogenesis and the presence of cancer stem cells (CSCs) are critical characteristics of tumors. In this study, we utilized cluster analysis and LASSO methods to assess the significance of angiogenesis‐ and stemness‐related genes in the efficacy of oncolytic virus (OV) immunotherapy.
Zhou L, Min Y, Cao Q, Tan X, Cui Y, Wang J.   +5 more
europepmc   +2 more sources

Identification and analysis of prognostic immune cell homeostasis characteristics in lung adenocarcinoma. [PDF]

Clin Respir J
Despite the presence of tumor markers in LUAD, studies based on genes associated with maintaining immune homeostasis have not been reported. We constructed a prognostic model of LUAD based on immune cell homeostasis‐related genes. LASSO and multivariate Cox regression were used to identify prognostic genes.
Sun Y, Ma Q, Chen Y, Liao D, Kong F.
europepmc   +2 more sources

Simultaneous Delivery of Doxorubicin and EZH2‐Targeting siRNA by Vortex Magnetic Nanorods Synergistically Improved Anti‐Tumor Efficacy in Triple‐Negative Breast Cancer

Small, Volume 19, Issue 43, October 25, 2023., 2023
A novel nanomedicine is synthesized based on Fe3O4 vortex nanorods loaded with doxorubicin (DOX) and EZH2 siRNAs and coated with a macrophage membrane. It shows a preferential tumor enrichment profile, thus leading to highly efficient drug delivery at the tumor site.
Yunshu Lu, Fenfen Gu, Yuwei Ma, Ruonan Li, Yi Luo, Xianhong Da, Lan Jiang, Xiang Li, Yan Liu   +8 more
wiley   +1 more source

Identification and Genomic Characterization of Anelloviruses in Patients with Chronic Lymphocytic Leukemia

Journal of Clinical Pharmacy and Therapeutics, Volume 2023, Issue 1, 2023., 2023
Purpose. Metagenomics has revealed that, in addition to the digestive tract, certain viruses are also commonly found in human blood. In order to explore and monitor potential novel viruses, three serum samples of patients with chronic lymphocytic leukemia were collected at the No. 2 People’s Hospital of Changshu City, China. Materials and Methods.
Tingwang Jiang, Qiang Liu, Fenying Lu, Teng He, Xiaoli Xiang, Zhicheng Zhang, Ying Sun, Pranshu Sahgal   +7 more
wiley   +1 more source

Primary prevention recommendations to reduce the risk of cognitive decline

Alzheimer's &Dementia, Volume 18, Issue 8, Page 1569-1579, August 2022., 2022
Abstract Introduction Few resources address steps clinicians can take to help patients reduce their risk of dementia, despite growing recognition that brain health can be optimized and that risk reduction for cognitive decline can be accomplished by lifestyle modifications.
Marwan N. Sabbagh, Adriana Perez, Thomas M. Holland, Malaz Boustani, Stephanie R. Peabody, Kristine Yaffe, Michelle Bruno, Russell Paulsen, Kelly O'Brien, Naila Wahid, Rudolph E. Tanzi   +10 more
wiley   +1 more source

Simulated patterns of mitochondrial diversity are consistent with partial population turnover in Bronze Age Central Europe

American Journal of Biological Anthropology, Volume 177, Issue 1, Page 134-146, January 2022., 2022
Abstract Objectives The analysis of ancient mitochondrial DNA from osteological remains has challenged previous conclusions drawn from the analysis of mitochondrial DNA from present populations, notably by revealing an absence of genetic continuity between the Neolithic and modern populations in Central Europe.
Nicolas Broccard, Nuno Miguel Silva, Mathias Currat   +2 more
wiley   +1 more source

First Ministry‐Academia Collaborative Report on Causes and Remedies of Human‐Animal Conflict at Hastinapur Wildlife Sanctuary, Uttar Pradesh, India

International Journal of Ecology, Volume 2022, Issue 1, 2022., 2022
Sustainable coexistence of different components of an ecosystem is a fundamental requirement for the overall welfare of the human population worldwide. Despite this fact, continued growth in human population, increasing demand for various available natural resources, and invasion of all inhabitable habitats have led to the destruction of the ...
Poonam Mishra, Anubha Chaudhary, Aayush Raj Tyagi, Anjali Gangwar, Anurag Tyagi, Mahima Singh, Megha Kaushik, Shambhavi Mishra, Yashi Garg, Yakshi Sethi, Himanshi Jain, Jyoti Pal, N. K. Janoo, Neelu Jain Gupta, Gowhar Meraj   +14 more
wiley   +1 more source

Single-cell and spatial transcriptomics reveal apelin/APJ pathway's role in microvessel formation and tumour progression in hepatocellular carcinoma. [PDF]

J Cell Mol Med
Abstract The apelin receptor (APJ) is a key player in tumour angiogenesis, but its role in hepatocellular carcinoma (HCC) remains unclear. This study aims to elucidate the function of the apelin/APJ pathway in HCC using a multi‐omics approach and identify potential therapeutic biomarkers.
Zhu Y, Zhang P, Huo X, Ling Y, Lv X, Lin S, Song H.   +6 more
europepmc   +2 more sources