Results 31 to 40 of about 1,647,972 (256)

Timing of the Granite magmatism, Wadi Abu Abid, North Eastern Desert, Egypt [PDF]

open access: yesAlfarama Journal of Basic & Applied Sciences
Granitic rocks represent a large portion of the Arabian-Nubian Shield (ANS) exposures in the North Eastern Desert (NED). The timing of the magmatic events plays a major role in illustrating the ANS development.
Mohamed Gharib   +3 more
doaj   +1 more source

KRITIK IBN WARRAQ ATAS ORIENTALISME EDWARD SAID: PERDEBATAN EPISTEMOLOGIS MENGENAI ‘TIMUR DAN BARAT’

open access: yes, 2019
This article tries to describe Ibn Warraq's critique onEdward Said's monumental work, "Orientalism (1979)" in four main areas; Said anti-Western; misunderstanding on Western culture; orientalism and imperialism; and the relationship of Western music ...
Bahri, Media Zainul
core   +1 more source

Clustering of diabetes: implications for personalized treatment

open access: yesКлинический разбор в общей медицине
Background. Diabetes mellitus traditionally classified into type 1, type 2, gestational, and other specific types. A novel five-cluster model severe autoimmune diabetes (SAID), severe insulin-deficient diabetes (SIDD), severe insulin-resistant diabetes ...
Khaled A. Abdel-Sater
doaj   +1 more source

Gaseous fuel diffusion flame with low oxygen concentrations

open access: yesResults in Engineering, 2023
The present study presents an experimental investigation into combustion characteristics of Liquefied Petroleum Gas (LPG) diffusion flame at air with low oxygen concentrations.
H.M. Gad   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Stress Analysis for Cylinder Made of FGM and Subjected to Thermo-Mechanical Loadings

open access: yesMetals, 2018
Functionally-graded materials (FGM) have recently been widely used. Furthermore, FGM are widely recommended in cylinder design. This study represents a mathematical analysis of the stresses and strains of an FGM cylinder.
El-Sayed Habib   +2 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Optimized CoQ10 delivery via ZnO/CuO nanoparticles: greater in vitro cell cycle arrest and in vivo tumor suppression than unformulated coenzyme Q10 [PDF]

open access: yesRSC Advances
Coenzyme Q10 (CoQ10) displays significant anticancer effects, but its potential medical application suffers from its inability to dissolve in water and low rates of absorption.
Lamiaa A. A. Barakat   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

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