Results 41 to 50 of about 705,347 (360)
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
On September 8, 1753 a celebration took place in the Wawel Cathedral to commemorate the five-hundredth anniversary of the canonisation of St. Stanislaus.
Marek Walczak
doaj +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
The aggravation of church relations and the transition to a visible confrontation between the Ecumenical Constantinople and the Moscow Patriarchate (up to the termination of the Eucharistic communion) is due to the urgent issue for all Ukrainians - the ...
archpriest Vasyl Lozovytski
doaj +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
VENERATING SHAYKH ABD AL-QADIR AL-JILANI IN INDONESIA AND TURKIYE
Shaykh Abd al-Qadir al-Jilani is a prominent figure in Muslim society. Compared to the influence of his intellectual works, the revered status he has earned is in large part because of his known outstanding spiritual qualities. He enjoys a place of honor
Imam Ghazali Said +3 more
doaj +1 more source
La mise en valeur de la zaouïa de Sidi Abu al-Hasan al-Karrây à Sfax
L’objet de cet article s’attache non seulement à la mise en valeur de la zaouïa de sidi Belhsan al-Karray, l’un des monuments le plus riche de la Medina de Sfax, mais aussi de documenter la méthodologie de la conservation-restauration de ce bien ...
Ammar Othman
doaj
Identifiant de l'operation archeologique : F1388200100020 Date de l'operation : 2001 (EV) C'est a la faveur des travaux d'amenagement de conduits souterrains de chauffage que des observations et des decouvertes ont ete realisees dans l'eglise paroissiale.
Salvini, Gilbert, Salvini, Gilbert
openaire +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source

