Results 51 to 60 of about 1,244,304 (272)
Mäetagused, 2010 Suur Vanker (‘the Great Wain’ in Estonian, the Big Dipper) is a commonly known constellation in Estonia. In addition to Suur Vanker, the astronym Hunt Härja kõrval ‘Wolf beside the Ox’ is one of the oldest written recordings of ethno-astronomic ...
Andres Kuperjanov
doaj
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Folia Historica Cracoviensia, 2003 On 8 September 1253 bishop Stanisław of Szczepanów was canonised in the basilica of St Francis at Assisi. A year later his relics were elevated to the altar in the centre of the crossing of the so-called second Romanesque cathedral on the ancient Wawel ...
Agnieszka Rożnowska-Sadraei
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Christian Feasts dedicated to Saints – an Interdisciplinary Perspective [PDF]
Annals of Philosophy, Social and Human Disciplines, 2012 Our paper is an interdisciplinary approach, of linguistic and theological analysis of a few lexemes that define saints who became popular in the Romanian culture and spirituality.
Carmen-Maria Bolocan
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Acadamies of Saint Louis University; Bulletin of Saint Louis University
, 2012 Saint Louis University Annual Catalog Volume 12 Number 6b of the 1916-1917 academic ...
Saint Louis University
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source