Results 81 to 90 of about 705,347 (360)

ECOLOGICAL SAINTS: ADOPTING A GREEN GAZE OF THE LIFE AND WRITINGS OF SAINT MARGUERITE BOURGEOYS

open access: yesZygon, 2023
During this time of ecological crisis, spiritual guides are needed to provide inspiration and impel action. In the Roman Catholic tradition, saints act as role models and are associated with particular causes, locations, or professions.
doaj   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

DEDİĞİ SULTAN MENAKIBNAMESİNDE TESPİT EDİLEN KERAMET MOTİFLERİ ÜZERİNE KÜLTÜREL BİR İNCELEME

open access: yesTürk Kültürü ve Hacı Bektaş Velî Araştırma Dergisi, 2023
Saints are the representatives who constitute the sacred side of the world in which they live and are thought to have extraordinary characteristics. Every element belonging to saints has been accepted as sacred and has been adopted as mediator between ...
Hasan SAVAŞ
doaj  

Cardinal Karol Wojtyla’s Care about Adequate Celebration of St. Stanislaus’ Jubilee (1971 -1979)

open access: yesFolia Historica Cracoviensia, 2003
“Polish Christian tradition linked two bishops and martyrs - witnesses, so to speak, of our Christening and Confirmation. From the point of view of the history of redemption - a spiritual process progressing through the history of a nation - it is still ...
Jan Szczepaniak
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

El concepto de θεῖος ἀνήρ en la antigüedad tardía. Hacia un nuevo marco definitorio = The Concept of θεῖος ἀνήρ in Late Antiquity. Towards a New Definitional Frame

open access: yesEspacio, Tiempo y Forma. Serie II, Historia Antigua, 2016
En el presente artículo nos aproximamos a la investigación de la figura del hombre divino —θεῖος ἀνήρ— en la Antigüedad Tardía con el objeto de aportar un nuevo marco definitorio del mismo.
Marco Alviz Fernández
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Hıristiyanlıkta Kutsal Mekanlarda Çaput Bağlama ve Bez Bırakma Pratikleri/Practices of Tying Rags and Leaving Cloths in Holy Places in Christianity

open access: yesOksident
Rituals performed at sacred sites in Christianity are among the important religious practices through which believers embody their spiritual bonds. These rituals, which have evolved throughout history, have reflected people's efforts to express their ...
Azize Uygun
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

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