Results 81 to 90 of about 673,928 (344)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Dede Korkut Kitabı’ndaki Dumrul’un Delilikten Velîliğe Tekâmül Yolculuğu

Diyanet İlmi Dergi
Türk halk kültür ve inancına dair önemli bulgular taşıyan Deli Dumrul destanında tasavvufî açıdan birçok unsura rastlanmıştır. Temel tasavvufî kavramların temsil edildiği birçok sembol ve ifadenin destan içerisinde, bir sistem dâhilinde sonuca yönelik ...
Musa Kaval
doaj   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Resource utilization and economic outcomes following repetitive transcranial magnetic stimulation for treatment-resistant depression: a retrospective observational analysis

Journal of Comparative Effectiveness Research
Aim: We investigated the impact of repetitive transcranial magnetic stimulation (rTMS) for treatmentresistant depression on healthcare resource utilization as well as commercial and Medicare Fee-for-Service payer costs. Materials & methods:We conducted
Joseph J Taylor, Andrew J Manett, Michael Feyder, Brandon S Bentzley   +3 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

La chanson de geste et le sacré, éd. N. Bragantini-Maillard, É. Goudeau, Fr. Laurent, Cl. Roussel, N. Viet, Clermont-Ferrand, Presses Universitaires Blaise Pascal, 2019

Perspectives Médiévales, 2021
Agata Sobczyk
doaj   +1 more source

Medieval cycles presenting the life and martyrdom of St. Stanislaus the Bishop and the miracles after his death

Folia Historica Cracoviensia, 2003
The author has presented the state of research on the works existing in Poland as well as the ones connected with the country. Then he has compiled and discussed the same theme scenes.
Zdzisław Kliś
doaj   +1 more source

M. Barré De Saint-Venant [PDF]

, 1886
Karl Pearson
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

The Name Stanislaus among Cracow Burghers until 1333

Folia Historica Cracoviensia, 2003
The name Stanislaus (or its diminutive form) appears in Cracow burghers’ families in which names that sounded German, Polish or Ruthenian were recorded.
Jerzy Rajman
doaj   +1 more source