Results 101 to 110 of about 277,402 (313)

Voorbeeldlevens van toen en nu

open access: yesNeerlandica Wratislaviensia
Wonderbaarlijke levens. Patronen in heiligenlevens by Ludo Jongen offers a richly illustrated and accessible exploration of medieval hagiography. Drawing on decades of research, Jongen examines recurring patterns in saints’ lives and their enduring ...
Małgorzata Dowlaszewicz
doaj   +1 more source

Joseph Taylor from Lincolnshire: a biography of a singer

open access: yes, 2004
Biographical account of Joseph Taylor of Saxby All Saints, Lincolnshire; he was one of the singers recorded by Percy Grainger in North Lincolnshire between 1905 and 1908.
Greig, Ruairidh
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

The Life of Aleksandr Men\u27: Hagiography in the Making

open access: yes, 1999
Hagiography is not an extinct genre in Russian literature, even though many believe that it was important in the history of early Russian literature but became irrelevant as Russian literature entered its modem period.
Wehrle, Janet M.
core  

Saint-Maximin-la-Sainte-Baume – Boulevard Saint-Jean, Saint-Simon

open access: yesADLFI. Archéologie de la France - Informations
Le terrain concerné par le diagnostic, situé à 300 m au sud-est de la ville médiévale, est cependant assez éloigné du pôle central des découvertes, concentrées au nord-ouest de cette dernière. De ce fait, peu de vestiges sont connus aux alentours proches.Le terrain concerné par le projet occupe une superficie de 7 993 m2, dont environ 2 500 n’étaient ...
Monteil, Karine, Monteil, Karine
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Paraphysical Jurisprudent Massacre Mediation [PDF]

open access: yes, 2015
It is possible and thereby feasible to develop and implement a pragmatic methodology for a preemptive evidentiary system of ‘Paraphysical Jurisprudence’ for mediating the occurrence of massacres.
Amoroso Richard, L.
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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