Results 81 to 90 of about 65,433 (290)

Saints Marching In, 1590-2009 [PDF]

open access: yes
The Catholic Church has been making saints for centuries, typically in a two-stage process featuring beatification and canonization. We analyze determinants of rates of beatification and canonization (for non-martyrs) over time and across six world ...
Robert J. Barro, Rachel M. McCleary
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

The Church in Densuş Between the Sacred and the Profane [PDF]

open access: yesAnastasis: Research in Medieval Culture and Art
Temple of Zamolxe, pagan Roman temple of the god Mars, mausoleum of Trajan’s best friend, the general Longinus Maximus, church built by the Goths in the 4th century, “divine work stolen by nocturnal genies”1, the first church in Haţeg and perhaps in the ...
Petruța Iulia Luchian
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

The Holy Land of Saints: The Latin Patriarchate of Jerusalem and the Life Story of St. Marie Alphonsine

open access: yesReligions
Utilizing the lens of new historicism, this study examines how hagiographers Stolz, Duvignau, and Khoury, from the Latin Patriarchate of Jerusalem, have constructed and modified the narrative identity of St.
Maayan Karen Raveh
doaj   +1 more source

Presentation "The Lavender Saints: LGBT Mormons Born Before 1869"

open access: yes, 2014
Powerpoint "The Lavender Saints: LGBT Mormons Born Before 1869" brief overview of some of the influential LGBTQIA+ people involved in the Church of Jesus Christ of Latter-day Saints or the early formation of the Deseret/Utah Territory.Converted from ...
Connell O\u27Donovan
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Making Saints in a “Glocal” Religion

open access: yes
Early modern Catholicism was a “glocal” affair: global in aspiration yet diverse in its local manifestations. Saint-making was no exception. In the wake of the Council of Trent, the Roman Church developed complex bureaucratic procedures through which the

core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

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