Results 61 to 70 of about 65,433 (290)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Treasury of Irish Saints, by John Irvine, page 13 Three Irish Saints

open access: yes, 1964
Image issued as illustration for The Dolmen Press, Dublin, Ireland, and printed in 1964.
Brandt, Ruth
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

[News Clip: All saints moves]

open access: yes, 1959
Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about patients from the All Saints hospital in Fort Worth being moved to the new ...
WBAP-TV (Television station : Fort Worth, Tex.)
core   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Beheaded bride and medieval romans: reinventing roman origins in the dossier of saint Valerie of Limoges (10th — 12th centuries) [PDF]

open access: yesВестник Православного Свято-Тихоновского гуманитарного университета: Серия ИИ. История, история Русской Православной Церкви
The paper revolves around Saint Valerie of Limoges, the local martyr, whose development into a figure of symbolic heiress of Roman Aquitaine can be traced through the hagiographic and iconographic tradition of the 10th – 12th centuries.
Vera Yarnykh
doaj   +1 more source

Hawaiian Flag quilt by Hawaiian Saints

open access: yes, 1916
Image of Hawaiian Flag quilt created in 1916 by Hawaiian Saints. Also includes questionnaires describing the quilt completed by Helen Pickett as part of the Utah Quilt Guild\u27s documentation days held from 1988-1994. See attached letter given as a gift
Hawaiian Saints
core  

Video Presentation "The Lavender Saints: LGBT Mormons Born Before 1869"

open access: yes, 2020
Video Powerpoint presentation "The Lavender Saints: LGBT Mormons Born Before 1869" brief title narration by Connell "Rocky" O\u27Donovan brief overview of some of the influential LGBTQIA+ people involved in the Church of Jesus Christ of Latter-day Saints
Connell O\u27Donovan
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

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