Results 71 to 80 of about 65,433 (290)

Making Public Knowledge — Making Knowledge Public

open access: yesJournal for the History of Knowledge, 2020
This article investigates the spread of inquisition as an influential administrative technique across thirteenth-century Europe in religious, civil, and governmental fields. It shows how by looking at the single life of Gui Foucois (d.
John Sabapathy
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

”Saint Paul” [PDF]

open access: yesThe Expository Times, 1891
n ...
openaire   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Catholic Martyrs and Canon Law: Reassessing the Meaning of Hagiographic Texts in Philip II’s Spain

open access: yesReligions
This essay is about the uses of martyrdom works in Spain and among Elizabethan English Catholics with special reference to their beatification cause by the Dicastery for the Causes of Saints. There are two related points in this essay.
Vittoria Feola
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Medieval Arles through the Lives of Its Founding Bishop

open access: yesReligions
Texts recounting the careers of saints were foundational to Christian worship and historical construction in medieval Europe. They were also fluid, living works that evolved over time as individual saints’ stories were revised, adapted, and retold. These
Samantha Kahn Herrick
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

The functions of religion and science in utopian thinking in the middle ages and the early modern period [PDF]

open access: yesBelgrade Philosophical Annual
This paper explores the ways in which religion and science - broadly defined - have been used to construct and imagine ideal societies in the medieval and early modern periods.
Hope Steffen
doaj   +1 more source

Home - About - Disclaimer - Privacy