Results 131 to 140 of about 277,402 (313)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Hagiography

open access: yes, 2015
Jon Boorstin proposes three purposes for film production – voyeuristic, vicarious, and visceral (Boorstin). Scrutinized in light of Boorstin’s proposal, hagiographical films are most likely to have three purposes imbedded in three generic types ...
Yang, Sunggu
core  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

October 1964 [PDF]

open access: yes, 1964
Dear Brother: If the faithful slaves in the mailing room have returned from their vacation, this will land on your desk sometime in early October. It is an interesting and somewhat dismaying fact in the life of the Church in the twentieth century that ...
Kretzmann, O.P.
core   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

St. Genevieve in the Revolution : Sylvain Maréchal’s Counter-History

open access: yesConserveries Mémorielles, 2013
Dr. Delany is author of many articles and books in medieval and early modern literature and culture including on Chaucer, Christine de Pizan, Elias Levita and others.
Sheila Delany
doaj  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Sainte parmi les saints

open access: yes, 2005
Au Maghreb, au XXIe siècle, les saints musulmans et les rituels qui leur sont associés, loin de se dissoudre dans une modernité uniformisante, continuent à réunir nombre de fidèles. À partir d’un travail de terrain de plusieurs années, à Tunis et à La Manouba, l’auteur analyse le culte contemporain d’une sainte du XIIIe siècle, Sayyda Mannûbiya.
openaire   +1 more source

Saint Petersburg – Leningrad – Saint Petersburg

open access: yesLidé města, 2009
A characteristic feature of the contemporary language of popular culture is an attempt to present Saint Petersburg in the categories of the superlative and greatness. A popular history of the city is based on a few selected events: 1. Founded in 1703 by Tsar Peter the Great who subsequently appointed himself emperor, the city gave rise to a new Russia ...
openaire   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

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