Results 41 to 50 of about 1,053,714 (315)

Outcomes and Surgical Management of Malignant Rhabdoid Tumor of the Kidney: A Report From the Pediatric Surgical Oncology Research Collaborative

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt   +76 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Interactions between gilthead seabream intestinal transcriptome and microbiota upon Enteromyxum leei infection: a multi–omic approach

open access: yesAnimal Microbiome
Background The enteric myxozoan parasite Enteromyxum leei is an important problem in gilthead seabream aquaculture invading the intestinal epithelium and leading to chronic intestinal inflammation, poor food conversion rates, cachexia, and mortalities ...
Socorro Toxqui-Rodríguez   +7 more
doaj   +1 more source

Sex- and stage-dependent expression of gonadal soma-derived factor paralogues reveals functional and evolutionary divergence in European sea bass (Dicentrarchus labrax)

open access: yesFrontiers in Endocrinology
IntroductionThe gonadal soma-derived factor (Gsdf) is a member of the Transforming Growth Factor-β (TGF-β) superfamily, with key roles in teleost reproduction, particularly in males.
Alessia Mascoli   +4 more
doaj   +1 more source

ABSORÇÃO DE ÓLEO DE SOJA E SÓDIO EM ARROZ E FEIJÃO PREPARADOS ABSORPTION OF SOYBEAN OIL AND SODIUM IN COOKED RICE AND BEANS

open access: yesPesquisa Agropecuária Tropical, 2007
<!-- @page { margin: 2cm } --> <p class="western" align="justify">O trabalho teve por objetivo avaliar a absorção de óleo de soja e sódio em arroz e feijão preparados, mediante análises de umidade, lipídios totais, sódio e da aceitabilidade ...
Sillsa da Costa Xavier   +3 more
doaj   +1 more source

Angle Preserving Mappings

open access: yes, 2015
In this paper, we give some characterizations of orthogonality preserving mappings between inner product spaces. Furthermore, we study the linear mappings that preserve some angles.
Frank, Michael   +2 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

General Anesthesia Control Mode Versus Local Anesthesia with Intravenous Sedation for Day Care Laparoscopic Tubal Ligation

open access: yesNational Journal of Community Medicine, 2011
Comparative study has been undertaken to evaluate the anaesthetic techniques either by General anaesthesia with control mode (GA) or Local anaesthesia with intravenous sedation (LA) in laparoscopic tubal ligation in 60 female patients in the age group ...
Dinesh Thakur   +2 more
doaj  

Etiquetado nutricional, ¿qué se sabe del contenido de sodio en los alimentos?

open access: yesRevista Médica Clínica Las Condes, 2015
La ingesta excesiva de sodio es una característica de nuestra alimentación, es un factor de riesgo de hipertensión arterial y de muerte por complicaciones cardiovasculares.
A. Carlos Saieh, Dr.   +3 more
doaj   +1 more source

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