Results 51 to 60 of about 1,668,727 (307)

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Evaluation Of Intravenous Propofol Anesthesia and Traditional Inhalational Anesthesia in Mastoid Surgery

National Journal of Community Medicine, 2011
The total intravenous anesthesia (TIVA) due to advent of Propofol for both induction and continuous intravenous maintenance of anesthesia avoids local & global pollution as seen in inhalation anesthestic agents1 and allows rapid recovery of ...
Nayna K Chavda, Dinesh Thakur, Mihir Goswami, Yogesh Chauhan, Himanshu Shah   +4 more
doaj  

Etiquetado nutricional, ¿qué se sabe del contenido de sodio en los alimentos?

Revista Médica Clínica Las Condes, 2015
La ingesta excesiva de sodio es una característica de nuestra alimentación, es un factor de riesgo de hipertensión arterial y de muerte por complicaciones cardiovasculares.
A. Carlos Saieh, Dr., B. Carlos Zehnder, Dr., C. Eu Magdalena Castro, MSc, Pablo Sanhueza, Dr.   +3 more
doaj   +1 more source

Change in Mental Health and Resilience in Childhood Cancer Survivors After Attending a Person‐Centred State‐of‐the‐Art Late Effects Clinic—on Behalf of the PanCareFollowUp Consortium

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Person‐centred follow‐up care based on evidence‐based clinical practice guidelines and providing individualised information should help to inform and reassure survivors about their medical and psychosocial situation and provide treatment and support where needed.
Gisela Michel, Mieke Rijken, Marietta Kokla, Charlotte Sleurs, Jurgen Lemiere, Line Elmerdahl Frederiksen, Luzius Mader, Cecilia Follin, Sara Oberti, Jeanette Falck Winther, Selina R. van den Oever, Leontien C. M. Kremer, Helena J. H. van der Pal, Peter Spreeuwenberg, Eline Bouwman, Jeroen te Dorsthorst, Samira Essiaf, Elizabeth A. M. (Lieke) Feijen, Hannah Gsell, Riccardo Haupt, Maria van Helvoirt, Rosella P. M. G. Hermens, Lars Hjorth, Tomas Kepak, Katerina Kepakova, Anita Kienesberger, Monica Muraca, Marleen Renard, Carina Schneider, Roderick Skinner, Anne Uyttebroeck, Deveny Vanrusselt, Sabine Verschueren, Jacqueline Loonen, Saskia M. F. Pluijm, Katharina Roser, the PanCareFollowUp consortium   +36 more
wiley   +1 more source

Search as Learning (SAL) Workshop 2016

Annual International ACM SIGIR Conference on Research and Development in Information Retrieval, 2016
The "Search as Learning" (SAL) workshop is focused on an area within the information retrieval field that is only beginning to emerge: supporting users in their learning whilst interacting with information content.
J. Gwizdka, P. Hansen, C. Hauff, Jiyin He, Noriko Kando   +4 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Interactions between gilthead seabream intestinal transcriptome and microbiota upon Enteromyxum leei infection: a multi–omic approach

Animal Microbiome
Background The enteric myxozoan parasite Enteromyxum leei is an important problem in gilthead seabream aquaculture invading the intestinal epithelium and leading to chronic intestinal inflammation, poor food conversion rates, cachexia, and mortalities ...
Socorro Toxqui-Rodríguez, Itziar Estensoro, Ricardo Domingo-Bretón, Raquel Del Pozo, Jaume Pérez-Sánchez, Detmer Sipkema, Ariadna Sitjà-Bobadilla, M. Carla Piazzon   +7 more
doaj   +1 more source

Transcriptomic profiling of Gh/Igf system reveals a prompted tissue-specific differentiation and novel hypoxia responsive genes in gilthead sea bream

Scientific Reports, 2021
A customized PCR-array was used for the simultaneous gene expression of the Gh/Igf system and related markers of muscle growth, and lipid and energy metabolism during early life stages of gilthead sea bream (60–127 days posthatching).
F. Naya-Català, P. Simó-Mirabet, J. Calduch-Giner, J. Pérez-Sánchez   +3 more
doaj   +1 more source

Salvianolic Acid B (Sal B) Protects Retinal Pigment Epithelial Cells from Oxidative Stress-Induced Cell Death by Activating Glutaredoxin 1 (Grx1)

International Journal of Molecular Sciences, 2016
Protein glutathionylation, defined as the formation of protein mixed disulfides (PSSG) between cysteine residues and glutathione (GSH), can lead to cell death.
Xiaobin Liu, Christy Xavier, J. Jann, Hongli Wu   +3 more
semanticscholar   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source