Results 51 to 60 of about 1,702,356 (260)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Beilstein Journal of NanotechnologyThe structural and physical properties of microencapsulated iron sucrose and their changes upon dissolution in saline were tested. For the undissolved sample, calcium alginate microcapsules with irregular shapes were registered via scanning electron ...
Sabina Lewińska +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Research and development progress report 705 [PDF]
, 1971 Report describing the MSF/VTEX Distillation Plants at the San Diego Test Facility of the Office of Saline Water for the purpose of advancing and developing the state of the art of flash distillation plants and thereby reducing the cost of seawater ...
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On the origin and pathway of the saline inflow to the Nordic Seas: insights from models [PDF]
, 2001 The behaviours of three high-resolution ocean circulation models of the North Atlantic, differing chiefly in their description of the vertical coordinate, are investigated in order to elucidate the routes and mechanisms by which saline water masses of ...
Herrmann, P. +7 more
core +1 more source
Comparison of different betadine and saline combinations on microorganisms: An original research
Journal of Pharmacy and Bioallied SciencesIntroduction: Pathogenic bacteria in the oral cavity or a physiological microbiome imbalance can cause or maintain disease. Thus, this work examined a novel betadine–saline combination for antibacterial and antifungal activities.
Kumari Seema +6 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Intermittent saline flushes or continuous saline infusion: what works better when heparin-free dialysis is recommended? [PDF]
, 2013 Edward Zimbudzi Department of Nephrology, Monash Health, Monash Medical Centre, Clayton, Melbourne, VIC, Australia Introduction: Coagulation-free dialysis, also commonly known as “heparin-free” dialysis, can be a challenging procedure as it ...
Zimbudzi E
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Alexandria Journal of MedicineBackground This study compared the effect of conventional doses of mannitol alone versus combined lower doses of mannitol-hypertonic saline on brain debulking during elective craniotomies.Patients and methods Sixty participants aged 18–60 years, ASA ...
Eslam Mohammed Ahmed El-Genaidy +4 more
doaj +1 more source
Journal of Orthopaedic Translation, 2017 In vitro and in vivo studies evidenced that mesenchymal stem cells (MSCs) contribute to intervertebral disc (IVD) regeneration by differentiation towards the disc phenotype and matrix synthesis and/or by paracrine signalling to endogenous cells, thereby ...
Marianna Peroglio +6 more
doaj +1 more source