Results 81 to 90 of about 3,024,565 (379)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Beilstein Journal of NanotechnologyThe structural and physical properties of microencapsulated iron sucrose and their changes upon dissolution in saline were tested. For the undissolved sample, calcium alginate microcapsules with irregular shapes were registered via scanning electron ...
Sabina Lewińska +7 more
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Uji Asosiasi Bakteri Rhizobium Terseleksi dengan Leguminosa Pakan dalam Kondisi Tercekam Salin
Jurnal Agripet, 2014 (Test of Association Selected Rhizobium Bacteria with Legumes in Salinity Stress) ABSTRACT. The research aim was to investigate association selected rhizobium bacteria with legumes in salinity stress.
Eny Fuskhah +3 more
doaj +1 more source
Saline Conversion and Ice Structures from Artificially Grown Sea Ice [PDF]
, 1967 The environment of cold regions is generally viewed as inhospitable, primarily due to application of ideal processes and techniques suitable to temperate zones. The work herein is a step toward solving two environmental problems.
Behlke, C. E. +2 more
core
Postsynaptic α1-Adrenergic vasoconstriction is impaired in young patients with vasovagal syncope and is corrected by nitric oxide synthase inhibition [PDF]
, 2016 BACKGROUND: Syncope is a sudden transient loss of consciousness and postural tone with spontaneous recovery; the most common form is vasovagal syncope (VVS).
Medow, MS +6 more
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Laryngoscope Investigative Otolaryngology, 2020 Objective To assess the efficacy of saline nasal irrigation (S‐NI) and xylitol nasal irrigation (X‐NI) for chronic rhinosinusitis in participants with Gulf War illness (GWI).
David Rabago +3 more
doaj +1 more source
Saline irrigation for allergic rhinitis.
Cochrane Database of Systematic Reviews, 2017 BACKGROUND Allergic rhinitis is a common condition affecting both adults and children. Patients experience symptoms of nasal obstruction, rhinorrhoea, sneezing and nasal itching, which may affect their quality of life.Nasal irrigation with saline (salty ...
K. Head +6 more
semanticscholar +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source