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Physiologic and hypertonic saline solutions impair ciliary activity in vitro

open access: yesThe Laryngoscope, 1999
AbstractObjective/Hypothesis: Physiologic saline (NaCl 0.9%) is commonly used in treating acute and chronic rhinosinusitis. Moreover, physiologic saline is used as a control medium, vehicle, or solvent in studies on ciliary beat frequency (CBF). Hypertonic saline (NaCl 7% and 14.4%) has been applied in attempts to enhance mucociliary transport in ...
Boek, W.M.   +3 more
openaire   +6 more sources
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Hypertonic saline solutions in brain injury

Current Opinion in Critical Care, 2004
Hypertonic saline solutions have received renewed attention as effective agents for the treatment of cerebral edema and in brain resuscitation in a variety of brain injury paradigms. Although evidence of the beneficial action of hypertonic saline solutions in traumatic brain injury is robust, data supporting use in other conditions are only now ...
Anish, Bhardwaj, John A, Ulatowski
openaire   +2 more sources

Cerebral edema: Hypertonic saline solutions

Current Treatment Options in Neurology, 1999
Our experience, and that of others, suggests that hypertonic saline solution therapy reduces intracranial pressure and lateral displacement of the brain in patients with cerebral edema. This therapy appears most promising in patients who have head trauma or postoperative cerebral edema.
, Bhardwaj, , Ulatowski
openaire   +2 more sources

Nebulised hypertonic saline solution for acute bronchiolitis in infants

Cochrane Database of Systematic Reviews, 2023
Airway oedema (swelling) and mucus plugging are the principal pathological features in infants with acute viral bronchiolitis. Nebulised hypertonic saline solution (≥ 3%) may reduce these pathological changes and decrease airway obstruction. This is an update of a review first published in 2008, and updated in 2010, 2013, and 2017.To assess the effects
Zhang, Linjie   +4 more
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EFFECTS OF HYPERTONIC SALINE SOLUTION ON MESENTERIC MICROCIRCULATION

Shock, 2001
We evaluated systemic and microvascular effects of hypertonic NaCl solution on normovolemic and hemorrhaged animals. Forty-three Wistar rats (186 +/- 4 g, mean +/- SEM) were anesthetized with pentobarbital and cannulated for mean arterial pressure (MAP), heart rate (HR), and mean pulse pressure (MPP) monitoring and blood withdrawal.
I P, Torres Filho   +3 more
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Saline versus glucose as a hypertonic solution for abortion

American Journal of Obstetrics and Gynecology, 1970
Abstract In this comparative study of the effectiveness and complications of therapeutic abortion induced by hypertonic solutions, 42 cases in which hypertonic glucose was used are contrasted with 134 cases in which hypertonic saline was used. If one is willing to accept the possible complications of inadvertent injection or absorption of saline into
W, Droegemueller, B E, Greer
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Effects of hypertonic saline solutions in the coronary circulation

Resuscitation, 1994
The use of small-volume injections of hypertonic saline solutions (HSS) in resuscitation from hemorrhagic shock is accompanied by well-maintained and pronounced increases in coronary blood flow (CBF) and by increases in myocardial contractility. The present study was performed in open-chest, anesthetized dogs to evaluate the contribution of direct ...
G J, Crystal   +5 more
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Mucociliary Clearance and Buffered Hypertonic Saline Solution

The Laryngoscope, 1997
AbstractNasal irrigations have been used for centuries without any scientific data to determine efficacy. For 10 years, the senior author has used buffered hypertonic saline nasal irrigation for patients with acute/chronic sinusitis and for those having undergone sinus surgery.
A R, Talbot, T M, Herr, D S, Parsons
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Influence of Hypertonic Saline Solution Infusion on Defibrillation Efficacy

Chest, 1996
Hypertonic saline solution may enhance cardiac conduction via the fast inward sodium channel and alter transmembrane Ca+2 conductance via the sodium-calcium exchanger. Evidence suggests that both Ca+2 conductance and myocardial conduction velocity may affect ventricular defibrillation. Since hypertonic saline solution solutions (ie, sodium bicarbonate)
M R, Ujhelyi   +6 more
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Dose Response Characteristics of Hypertonic Saline Dextran Solutions

The Journal of Trauma: Injury, Infection, and Critical Care, 1991
In an effort to find the best hypertonic saline-dextran solution (HSD) for prehospital use, 33 chronically catheterized sheep were bled using a fixed pressure shock model (50 mm Hg x 2 hours) and resuscitated with 4 ml/kg of HSD solution (2-minute bolus).
L, Halvorsen   +3 more
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