Results 91 to 100 of about 947,047 (350)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Coping with salinity in irrigated agriculture: Crop evapotranspiration and water management issues

, 2020
Soil and water salinity and associated problems are a major challenge for global food production. Strategies to cope with salinity include a better understanding of the impacts of temporal and spatial dynamics of salinity on soil water balances vis-a-vis
P. Minhas, T. Ramos, Alon Ben-Gal, L. S. Pereira   +3 more
semanticscholar   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Effects of sodic water irrigation on growth, physiological relations and ion uptake in two Ziziphus rootstocks

The Indian Journal of Agricultural Sciences, 2018
We studied the effects of sodic irrigation on growth, physiological parameters and mineral partitioning in Zizyphus rotundifolia (ZR) and Z. spina-christi (ZS) seedlings used as rootstocks for Indian jujube scion cultivars.
ANSHUMAN SINGH, ASHWANI KUMAR, RAJKUMAR RAJKUMAR, PARVENDER SHEORAN, R K YADAV   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Performance of edible cactus (Opuntiaficus-indica) in saline environments

The Indian Journal of Agricultural Sciences, 2014
Edible cactus [Opuntiaficus-indica (L.) Mill.] has been used as fruit, vegetable, forage and wide range of commercial purposes in arid regions. It has high efficiency to produce biomass per unit water use due to specialized photosynthetic mechanism ...
GAJENDER GAJENDER, GURBACHAN SINGH, J C DAGAR, KHAJANCHI LAL, R K YADAV   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Diurnal changes and effect of elevated CO2 on gas exchange under individual and interactive salt and water stress in wheat (Triticum aestivum)

The Indian Journal of Agricultural Sciences, 2019
To evaluate the individual and interactive effects of drought and salt stress on diurnal stomatal behaviour and gas exchange parameters, two salt tolerant (Kharchia 65, KRL 210) and two salt sensitive (HD 2851, HD 2009) wheat (Triticum aestivum L ...
ASHWANI KUMAR, AJAY KUMAR MISHRA, KAILASH SINGH, CHARU LATA, ARVIND KUMAR, KRISHNAMURTY S L, PARVEEN KUMAR   +6 more
doaj   +1 more source

Effect of salinity and temperature on broodstock conditioning of mangrove clam Polymesoda erosa (Solander, 1786) [PDF]

, 2021
Bhatkar VR, Pawase As, Pai R, Shirdhankar MS, DI Pathan   +4 more
openalex   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source