Results 91 to 100 of about 692,226 (362)

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Effects of sodic water irrigation on growth, physiological relations and ion uptake in two Ziziphus rootstocks

The Indian Journal of Agricultural Sciences, 2018
We studied the effects of sodic irrigation on growth, physiological parameters and mineral partitioning in Zizyphus rotundifolia (ZR) and Z. spina-christi (ZS) seedlings used as rootstocks for Indian jujube scion cultivars.
ANSHUMAN SINGH, ASHWANI KUMAR, RAJKUMAR RAJKUMAR, PARVENDER SHEORAN, R K YADAV   +4 more
doaj   +1 more source

Recent changes in the surface salinity of the North Atlantic subpolar gyre [PDF]

, 2002
Sea surface salinity (SSS) was measured since 1896 along 60°N between Greenland and the North Sea and since 1993 between Iceland and Newfoundland. Along 60°N away from the shelves, and north of 53°N, the amplitude of the seasonal cycle is comparable to ...
Bacon, Bacon, Bauer, Belkin, Belkin, Bersch, Bojariu, Bretherton, Caniaux, Curry, Dickson, Dickson, Ducet, Eden, Eden, Esselborn, F. Schott, Fabien Durand, Gammelsrød, Gammelsrød, Gilles Reverdin, H. Valdimarsson, Hansen, Hilmer, Häkkinen, Häkkinen, Häkkinen, John Mortensen, Knudsen, Koltermann, Kushnir, Kwok, Lavender, Lazier, Levitus, Levitus, Marsden, Mauritzen, Mysak, Reverdin, Reverdin, Reverdin, Smed, Sutton, Taylor, Verbrugge, Vinje, W. Zenk   +47 more
core   +1 more source

Salines in Appendicitis [PDF]

The Boston Medical and Surgical Journal, 1893
n ...
openaire   +2 more sources

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Transitioning From Soil‐Based to Soil‐Foliar Hybrid Application for Nitrogen Fertilizers Offers Energy‐Saving and Use‐Efficiency Benefits

Food and Energy Security
Nitrogen (N) is the most important nutrient for crop plants to achieve their yield potential, yet it is also recognized as a major pollutant of the environment due to often‐excessive N‐fertilizer use.
Ajay Kumar Bhardwaj, Kapil Malik, Manu Rani, Ashwani Kumar, Sunita Devi, Naresh Kumar, Raj Kumar, Anita Mann, Parvender Sheoran, Uttam Kumar Mandal, Rajender Kumar Yadav   +10 more
doaj   +1 more source

Predicting the Success of Invasive Species in the Great Bay Estuarine Researve [PDF]

, 2007
The University of New Hampshire Zoology Department reports on a study designed to continue monitoring the distribution of invasive species in the Great Bay Estuary and to carry out laboratory experiments designed to test the effects of salinity on ...
Dijkstra, Jennifer A., Harris, Larry G.
core   +2 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Factors affecting estuarine populations of Nereocystis luetkeana in Kachemak Bay, Alaska [PDF]

, 2003
Thesis (M.S.) University of Alaska Fairbanks, 2003Nereocystis luetkeana forms extensive kelp beds in Kachemak Bay, Alaska. Salinity and turbidity gradients apparently regulate kelp bed distribution throughout this estuary.
Chenelot, Héloïse Anne Claude
core  

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source