Results 91 to 100 of about 1,306,008 (359)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

A multi-dimensional analysis of integrated farming system in salt-affected ecologies

open access: yesThe Indian Journal of Agricultural Sciences
The horizontal expansion of the arable areas seems infeasible with dwindling natural resources and declining the average size of landholdings. For harnessing the economic, environmental and social benefits of vertical expansion, the Integrated Farming ...
RAJKUMAR   +8 more
doaj   +1 more source

Biochemical changes in guava (Psidium guajava) cv. Allahabad Safeda fruits as a function of maturity stages

open access: yesThe Indian Journal of Agricultural Sciences, 2016
The effects of maturity stage and harvesting season were investigated on fruit quality attributes like total antioxidant activity (DPPH), total flavanoids, total phenolics, H2O2 scavenging activity and ascorbic acid content in fruits of guava (Psidium ...
RAJKUMAR RAJKUMAR   +5 more
doaj   +1 more source

Mechanism of Salinity Tolerance in Plants: Physiological, Biochemical, and Molecular Characterization

open access: yesInternational Journal of Genomics, 2014
Salinity is a major abiotic stress limiting growth and productivity of plants in many areas of the world due to increasing use of poor quality of water for irrigation and soil salinization.
Bhaskar Gupta, Bingru Huang
semanticscholar   +1 more source

Salinity Stress in Wheat: Effects, Mechanisms and Management Strategies

open access: yes, 2021
Salinity stress is a major threat to global food production and its intensity is continuously increasing because of anthropogenic activities. Wheat is a staple food and a source of carbohydrates and calories for the majority of people across the globe ...
M. Seleiman   +11 more
semanticscholar   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Water and soil salinity management and Sslt redistribution in irrigation systems [PDF]

open access: yes, 2006
Soil salinity is present in most of the large irrigation schemes over the world under the conjunctive effect of low quality irrigation water, aridity and lack of natural drainage ofsoils and aquifers.
Bouarfa, Sami   +8 more
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Impact of water deficit (salt and drought) stress on physiological, biochemical and yield attributes on wheat (Triticum aestivum) varieties

open access: yesThe Indian Journal of Agricultural Sciences, 2018
This investigation was carried out to assess the combined effect of salt stress and drought on physiological and biochemical traits in wheat (Triticum aestivum L.) varieties so as to deduce the probable mechanism of stress tolerance in these varieties ...
ASHWANI KUMAR   +7 more
doaj   +1 more source

de novo transcriptomic profiling of differentially expressed genes in grass halophyte Urochondra setulosa under high salinity

open access: yesScientific Reports, 2021
Soil salinity is one of the major limiting factors for crop productivity across the world. Halophytes have recently been a source of attraction for exploring the survival and tolerance mechanisms at extreme saline conditions.
Anita Mann   +10 more
doaj   +1 more source

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