Results 71 to 80 of about 292,464 (315)
Nitrogen (N) is the most important nutrient for crop plants to achieve their yield potential, yet it is also recognized as a major pollutant of the environment due to often‐excessive N‐fertilizer use.
Ajay Kumar Bhardwaj +10 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Evaluation of salinity tolerance in fourteen selected pistachio (Pistacia vera L.) cultivars
Cultivars and rootstocks tolerant to salinity are determinant toincrease the salt tolerance of planted fruit trees including pistachio. In this research, the effect of salinity stress on morphological and physiological traits as well as the concentration
Momenpour, Ali; National Salinity Research Center, Agricultural Research, Education and Extension Organization (AREEO), Yazd, Iran. +1 more
core +1 more source
Performance of edible cactus (Opuntiaficus-indica) in saline environments
Edible cactus [Opuntiaficus-indica (L.) Mill.] has been used as fruit, vegetable, forage and wide range of commercial purposes in arid regions. It has high efficiency to produce biomass per unit water use due to specialized photosynthetic mechanism ...
GAJENDER GAJENDER +4 more
doaj +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Salinity-Based Molecular Communication in Microfluidic Channels
In this work, we present a novel portable, flexible and easy-to-use experimental setup for investigating salinity- based information transmission in microfluidic channels.
Max Bartunik +13 more
core +1 more source
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Options for salinity mitigation in the Murray-Darling Basin [PDF]
The Murray-Darling Basin faces increasing pressure on water quantity and quality. In 2006-07, salt interception schemes implemented as part of the Murray–Darling Basin Salinity Management strategy removed over 470,000 tonnes of salt from the water supply,
Peggy Schrobback +2 more
core
In agricultural contexts, the presence of per- and polyfluoroalkyl substances (PFASs) in recycled water may pose a threat to irrigated crops and the human food chain.
Pia Ramos +3 more
doaj +1 more source

