Results 51 to 60 of about 137,017 (266)

A multi-dimensional analysis of integrated farming system in salt-affected ecologies

The Indian Journal of Agricultural Sciences
The horizontal expansion of the arable areas seems infeasible with dwindling natural resources and declining the average size of landholdings. For harnessing the economic, environmental and social benefits of vertical expansion, the Integrated Farming ...
RAJKUMAR, SURESH KUMAR, RAM KISHOR FAGODIYA, AWTAR SINGH, PARVENDER SHEORAN, GAJENDER YADAV, NIRMAL SINGH, SUBHASIS MANDAL, R K YADAV   +8 more
doaj   +1 more source

Salinity and drought induced changes in gas exchange attributes and chlorophyll fluorescence characteristics of rice (Oryza sativa) varieties

The Indian Journal of Agricultural Sciences, 2016
The present study was conducted to assess the effect of water deficit coupled with salt stress on physiological traits and stress tolerance mechanisms of rice (Oryza sativa L.) varieties differing in salt tolerance.
ASHWANI KUMAR, CHARU LATA, PARVEEN KUMAR, RITU DEVI, KAILASH SINGH, S L KRISHNAMURTHY, NEERAJ KULSHRESHTHA, RAJENDER K YADAV, SURINDER K SHARMA   +8 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Biochemical changes in guava (Psidium guajava) cv. Allahabad Safeda fruits as a function of maturity stages

The Indian Journal of Agricultural Sciences, 2016
The effects of maturity stage and harvesting season were investigated on fruit quality attributes like total antioxidant activity (DPPH), total flavanoids, total phenolics, H2O2 scavenging activity and ascorbic acid content in fruits of guava (Psidium ...
RAJKUMAR RAJKUMAR, GURPREET KAUR, ANITA MANN, CHARU LATA, ANSHUMAN SINGH, ASHWANI KUMAR   +5 more
doaj   +1 more source

de novo transcriptomic profiling of differentially expressed genes in grass halophyte Urochondra setulosa under high salinity

Scientific Reports, 2021
Soil salinity is one of the major limiting factors for crop productivity across the world. Halophytes have recently been a source of attraction for exploring the survival and tolerance mechanisms at extreme saline conditions.
Anita Mann, Naresh Kumar, Ashwani Kumar, Charu Lata, Arvind Kumar, Babu Lal Meena, Dwijesh Mishra, Monendra Grover, Sonam Gaba, C. Parameswaran, Nitin Mantri   +10 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Prolonged alkali water irrigation: impacts of treatment strategies on soil health and microbial dynamics

Ecological Processes
Background The extent of natural salt-laden groundwaters used for irrigation is increasing worldwide, which is a fast-emerging threat to agroecosystems and global food security.
Kirti Yadav, Awtar Singh, Neeraj K. Aggarwal, Gajender Yadav, Nirmalendu Basak, Ajay Kumar Bhardwaj, Rajender Kumar Yadav   +6 more
doaj   +1 more source

Standardization of the fourier transform near-infrared reflectance spectroscopy for estimation of some oil quality parameters in mustard (Brassica spp.)

Plant, Soil and Environment, 2013
The possibility of the application of the fourier transform near-infrared reflectance spectroscopy (NIRS) to the analysis of the selected quality parameters in the mustard oil was followed to determine oil, protein, erucic acid and crude fibre content at
J. Singh, P.C. Sharma, S.K. Sharma, A. Kumar   +3 more
doaj   +1 more source