Results 41 to 50 of about 137,017 (266)

Alfalfa MsSOS2 confers salinity tolerance by promoting lateral root growth and regulating Na+/K+ homeostasis

Scientific Reports
Salinity is a major abiotic stress limiting plant productivity. The Salt Overly Sensitive (SOS) pathway, comprising SOS1, SOS2, and SOS3, is central to ion homeostasis under salt stress. While the pathway has been extensively studied in model plants, its
Biswa R. Acharya, Lorenso A. R. Reyes, Lipsa Mishra, Jorge F. S. Ferreira, Todd H. Skaggs, Devinder Sandhu   +5 more
doaj   +1 more source

Comparative genomics reveals the molecular mechanism of salt adaptation for zoysiagrasses

BMC Plant Biology, 2022
Background Zoysiagrass (Zoysia spp.) is a warm-season turfgrass. It is widely used as turfgrasses throughout the world, offers good turf qualities, including salt tolerance, resistance to drought and heat.
Wei Wang, An Shao, Xiao Xu, Shugao Fan, Jinmin Fu   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Phosphorus-solubilizing fungi improve growth and P nutrition in sorghum at variable salinity levels

Environmental Microbiome
Background Salt–tolerant phosphorus solubilizing fungi (PSF) play a pivotal role in plant growth promotion and P–nutrition in saline agro–ecoregions. Isolation and characterization of salt–tolerant fungi with P-solubilizing potential and plant growth ...
Priyanka Chandra, Arvind Kumar Rai, Nirmalendu Basak, Parul Sundha, Kailash Prajapat, Awtar Singh, Anita Mann, R. K. Yadav   +7 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Understanding the salt overly sensitive pathway in Prunus: Identification and characterization of NHX, CIPK, and CBL genes

The Plant Genome
Salinity is a major abiotic stress factor that can significantly impact crop growth, and productivity. In response to salt stress, the plant Salt Overly Sensitive (SOS) signaling pathway regulates the homeostasis of intracellular sodium ion concentration.
Biswa R. Acharya, Chaoyang Zhao, Lorenso Antonio Rodriguez Reyes, Jorge F. S. Ferreira, Devinder Sandhu   +4 more
doaj   +1 more source

Assessing long term impact of nutrient management and rainfall variability on the agroecological resilience of maize (Zea mays)- wheat (Triticum aestivum) system in NW India

The Indian Journal of Agricultural Sciences, 2016
A long-term (2000-2010) field experiment was carried out in the lower Shiwalik foothills of Punjab to study the carry over effect of organic manures and fertilizers on the productivity of maize (Zea mays L.)- wheat (Triticum aestivum L.) cropping system
P SHEORAN, SHER SINGH, S S BAWA, V SARDANA, ASHWANI KUMAR, RAJKUMAR, B BHUSHAN, G S DHERI   +7 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Temporal variations in morpho-physiology of sandalwood and gene expression analysis revealed Shisham as host preference under water deficit and salinity stress

BMC Plant Biology
Background Sandalwood (Santalum album L.), a valuable aromatic tree species, faces significant growth and physiological challenges under abiotic stresses like water deficit and salinity, especially when both stressors are present. Host plant associations
Ashwani Kumar, Aarju Sharma, Shruti Kaushik, Antim Kundu, Pooja Dhansu, Kamlesh Verma, Raj Kumar, Abdulaziz Abdullah Alsahli, Parvender Sheoran   +8 more
doaj   +1 more source