Results 61 to 70 of about 596,146 (265)

Salinity and drought induced changes in gas exchange attributes and chlorophyll fluorescence characteristics of rice (Oryza sativa) varieties

open access: yesThe Indian Journal of Agricultural Sciences, 2016
The present study was conducted to assess the effect of water deficit coupled with salt stress on physiological traits and stress tolerance mechanisms of rice (Oryza sativa L.) varieties differing in salt tolerance.
ASHWANI KUMAR   +8 more
doaj   +1 more source

Dynamics of a salinity-prone agricultural catchment driven by markets, farmers' attitude and climate change [PDF]

open access: yes, 2007
An agent-based simulation model has been developed with CORMAS combining simplified bio-physical processes of land cover, dry-land salinity changes, rainfall, farm profitability and farmer decisions on land uses in a dry-land agricultural catchment (no ...
Asseng, S.   +4 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Temporal variations in morpho-physiology of sandalwood and gene expression analysis revealed Shisham as host preference under water deficit and salinity stress

open access: yesBMC Plant Biology
Background Sandalwood (Santalum album L.), a valuable aromatic tree species, faces significant growth and physiological challenges under abiotic stresses like water deficit and salinity, especially when both stressors are present. Host plant associations
Ashwani Kumar   +8 more
doaj   +1 more source

A multi-dimensional analysis of integrated farming system in salt-affected ecologies

open access: yesThe Indian Journal of Agricultural Sciences
The horizontal expansion of the arable areas seems infeasible with dwindling natural resources and declining the average size of landholdings. For harnessing the economic, environmental and social benefits of vertical expansion, the Integrated Farming ...
RAJKUMAR   +8 more
doaj   +1 more source

Biochemical changes in guava (Psidium guajava) cv. Allahabad Safeda fruits as a function of maturity stages

open access: yesThe Indian Journal of Agricultural Sciences, 2016
The effects of maturity stage and harvesting season were investigated on fruit quality attributes like total antioxidant activity (DPPH), total flavanoids, total phenolics, H2O2 scavenging activity and ascorbic acid content in fruits of guava (Psidium ...
RAJKUMAR RAJKUMAR   +5 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Impact of water deficit (salt and drought) stress on physiological, biochemical and yield attributes on wheat (Triticum aestivum) varieties

open access: yesThe Indian Journal of Agricultural Sciences, 2018
This investigation was carried out to assess the combined effect of salt stress and drought on physiological and biochemical traits in wheat (Triticum aestivum L.) varieties so as to deduce the probable mechanism of stress tolerance in these varieties ...
ASHWANI KUMAR   +7 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

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