Results 101 to 110 of about 805,968 (347)

Enhanced rice salinity tolerance via CRISPR/Cas9-targeted mutagenesis of the OsRR22 gene

Molecular breeding, 2019
Salinity is one of the most important abiotic stress affecting the world rice production. The cultivation of salinity-tolerant cultivars is the most cost-effective and environmentally friendly approach for salinity control.
A. Zhang, Yi Liu, Feiming Wang, Tianfei Li, Zhihao Chen, Deyan Kong, J. Bi, Fenyun Zhang, Xingxing Luo, Jiahong Wang, Jinjuan Tang, Xinqiao Yu, Guolan Liu, L. Luo   +13 more
semanticscholar   +1 more source

Groundwater Salinization in France

Procedia Earth and Planetary Science, 2013
AbstractThe state, sources, and vectors of salinity in French aquifers are assessed through a GIS-based approach and a literature review of geochemical studies. Seawater intrusion is dominant in the insular context, but the most impacted water bodies are inland aquifers affected by WRI with Permian to Tertiary evaporites, mixing with primary and ...
Kloppmann, W., Bourhane, A., Schomburgk, S.   +2 more
openaire   +3 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Synergy of reduced gypsum and pressmud – a cost effective approach for sustainable reclamation of degraded sodic lands

The Indian Journal of Agricultural Sciences, 2019
The effect of improved practice [IP; gypsum application @ 25% gypsum requirement (GR) +10 t/ha press mud] over existing practice (EP; gypsum application @ 50% GR) on rice productivity and profitability in sodic soils (pH 9.2-10.4) was evaluated at ...
YASH PAL SINGH, VINAY K MISHRA, AJAY K BHARADWAJ, SANJAY ARORA, ATUL K SINGH, SUDHANSHU SINGH, U S SINGH, A M ISMAIL, S M HAEFELE   +8 more
doaj   +1 more source

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Biochar selection for removal of perfluoroalkyl substances from reclaimed water for agricultural irrigation

Biochar
In agricultural contexts, the presence of per- and polyfluoroalkyl substances (PFASs) in recycled water may pose a threat to irrigated crops and the human food chain.
Pia Ramos, Michael P. Schmidt, Richeng Xuan, Daniel J. Ashworth   +3 more
doaj   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Evaluation of guava (Psidium guajava) and bael (Aegle marmelos) under shallow saline watertable conditions

The Indian Journal of Agricultural Sciences, 2018
Growth, physiological activities and leaf ionic relations were studied in guava (Psidium guajava L.) cv. Allahabad Safeda and bael (Aegle marmelos Correa) cv. NB-5 planted under shallow saline watertable conditions.
ANSHUMAN SINGH, ASHWANI KUMAR, ASHIM DATTA, R K YADAV   +3 more
doaj   +1 more source