Results 101 to 110 of about 947,047 (350)

Biochar selection for removal of perfluoroalkyl substances from reclaimed water for agricultural irrigation

Biochar
In agricultural contexts, the presence of per- and polyfluoroalkyl substances (PFASs) in recycled water may pose a threat to irrigated crops and the human food chain.
Pia Ramos, Michael P. Schmidt, Richeng Xuan, Daniel J. Ashworth   +3 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Differential Sensitivity of Chloroplasts in Mesophyll and Bundle Sheath Cells in Maize, an NADP-Malic Enzyme-Type C₄ Plant, to Salinity Stress [PDF]

, 2005
Rusdi Hasan, Youichiro Ohnuki, Michio Kawasaki, Mitsutaka Taniguchi, Hiroshi Miyake   +4 more
openalex   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Author response for "Low‐salinity transitions drive abrupt microbial response to sea‐level change"

, 2021
Alex Whittle, Robert L. Barnett, Dan J. Charman, Angela Gallego‐Sala   +3 more
openalex   +1 more source

Metabolic adaptations leading to lignification in wheat roots under salinity stress [PDF]

, 2023
Bhagya M. Dissanayake, Christiana Staudinger, Kosala Ranathunge, Rana Munns, Thusitha Rupasinghe, Nicolas L. Taylor, A. Harvey Millar   +6 more
openalex   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Decision letter for "Variation in salinity tolerance and water use strategies in an introduced woody halophyte ( Tamarix spp.)"

, 2021

openalex   +1 more source

Role of Chemical Additives in Plant Salinity Stress Mitigation [PDF]

, 2023
Priya Yadav, Mohammad Wahid Ansari, Narendra Tuteja   +2 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source