Results 111 to 120 of about 1,306,008 (359)

Strategic Switching from Conventional Urea to Nano-Urea for Sustaining the Rice–Wheat Cropping System

Plants
In the face of declining crop yields, inefficient fertilizer usage, nutrient depletion, and limited water availability, the efficiency of conventional NPK fertilizers is a critical issue in India.
Ashwani Kumar, Parvender Sheoran, Sunita Devi, Naresh Kumar, Kapil Malik, Manu Rani, Arvind Kumar, Pooja Dhansu, Shruti Kaushik, Ajay Kumar Bhardwaj, Anita Mann, Rajender Kumar Yadav   +11 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Recent changes in the surface salinity of the North Atlantic subpolar gyre [PDF]

, 2002
Sea surface salinity (SSS) was measured since 1896 along 60°N between Greenland and the North Sea and since 1993 between Iceland and Newfoundland. Along 60°N away from the shelves, and north of 53°N, the amplitude of the seasonal cycle is comparable to ...
Bacon, Bacon, Bauer, Belkin, Belkin, Bersch, Bojariu, Bretherton, Caniaux, Curry, Dickson, Dickson, Ducet, Eden, Eden, Esselborn, F. Schott, Fabien Durand, Gammelsrød, Gammelsrød, Gilles Reverdin, H. Valdimarsson, Hansen, Hilmer, Häkkinen, Häkkinen, Häkkinen, John Mortensen, Knudsen, Koltermann, Kushnir, Kwok, Lavender, Lazier, Levitus, Levitus, Marsden, Mauritzen, Mysak, Reverdin, Reverdin, Reverdin, Smed, Sutton, Taylor, Verbrugge, Vinje, W. Zenk   +47 more
core   +1 more source

Soil Salinity: Historical Perspectives and a World Overview of the Problem

, 2018
Soil salinity is not a recent phenomenon, it has been reported since centuries where humanity and salinity have lived one aside the other. A good example is from Mesopotamia where the early civilizations first flourished and then failed due to human ...
S. Shahid, M. Zaman, L. Heng
semanticscholar   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Measuring the Long-Term Regional Benefits of Salinity Reduction [PDF]

Approaches for evaluating salinity management benefits are generalized and extended to incorporate consideration of desalination and long-term changes in salinity concentration and water use patterns.
Bedient, Philip B., Characklis, Gregory W., Griffin, Ronald C.   +2 more
core   +1 more source

Evaluating physiological responses of plants to salinity stress

Annals of Botany, 2016
Background Because soil salinity is a major abiotic constraint affecting crop yield, much research has been conducted to develop plants with improved salinity tolerance. Salinity stress impacts many aspects of a plant’s physiology, making it difficult to
S. Negrão, Sandra M. Schmöckel, M. Tester   +2 more
semanticscholar   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Transitioning From Soil‐Based to Soil‐Foliar Hybrid Application for Nitrogen Fertilizers Offers Energy‐Saving and Use‐Efficiency Benefits

Food and Energy Security
Nitrogen (N) is the most important nutrient for crop plants to achieve their yield potential, yet it is also recognized as a major pollutant of the environment due to often‐excessive N‐fertilizer use.
Ajay Kumar Bhardwaj, Kapil Malik, Manu Rani, Ashwani Kumar, Sunita Devi, Naresh Kumar, Raj Kumar, Anita Mann, Parvender Sheoran, Uttam Kumar Mandal, Rajender Kumar Yadav   +10 more
doaj   +1 more source

Challenges for the development of a biotic ligand model predicting copper toxicity in estuaries and seas [PDF]

, 2012
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2011 SETAC.An effort is ongoing to develop a biotic ligand model (BLM) that predicts copper (Cu) toxicity in estuarine and marine ...
de Polo, A, Scrimshaw, MD
core   +1 more source