Results 131 to 140 of about 1,245,388 (394)
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Water and soil salinity management and Sslt redistribution in irrigation systems [PDF]
, 2006 Soil salinity is present in most of the large irrigation schemes over the world under the conjunctive effect of low quality irrigation water, aridity and lack of natural drainage ofsoils and aquifers.
Bouarfa, Sami +8 more
core
Enhanced rice salinity tolerance via CRISPR/Cas9-targeted mutagenesis of the OsRR22 gene
Molecular breeding, 2019 Salinity is one of the most important abiotic stress affecting the world rice production. The cultivation of salinity-tolerant cultivars is the most cost-effective and environmentally friendly approach for salinity control.
A. Zhang +13 more
semanticscholar +1 more source
Groundwater Salinization in France
Procedia Earth and Planetary Science, 2013 AbstractThe state, sources, and vectors of salinity in French aquifers are assessed through a GIS-based approach and a literature review of geochemical studies. Seawater intrusion is dominant in the insular context, but the most impacted water bodies are inland aquifers affected by WRI with Permian to Tertiary evaporites, mixing with primary and ...
Kloppmann, W. +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Performance of edible cactus (Opuntiaficus-indica) in saline environments
The Indian Journal of Agricultural Sciences, 2014 Edible cactus [Opuntiaficus-indica (L.) Mill.] has been used as fruit, vegetable, forage and wide range of commercial purposes in arid regions. It has high efficiency to produce biomass per unit water use due to specialized photosynthetic mechanism ...
GAJENDER GAJENDER +4 more
doaj +1 more source
Stochastic modeling of soil salinity [PDF]
, 2010 A minimalist stochastic model of primary soil salinity is proposed, in which the rate of soil salinization is determined by the balance between dry and wet salt deposition and the intermittent leaching events caused by rainfall events.
Daly, E. +4 more
core +2 more sources
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Options for salinity mitigation in the Murray-Darling Basin [PDF]
The Murray-Darling Basin faces increasing pressure on water quantity and quality. In 2006-07, salt interception schemes implemented as part of the Murray–Darling Basin Salinity Management strategy removed over 470,000 tonnes of salt from the water supply,
David Adamson +2 more
core
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source