Results 81 to 90 of about 692,226 (362)

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Bio-physicochemical Markers of the Aedes Aegypti Breeding Water in Endemic and Non-endemic Area [PDF]

, 2019
The survival of Aedes aegypti larvae is inseparable from the adequacy of food, including organic substances available in the breeding water. It is very dependent on the level of water markers such as temperature, salinity, Dissolved Oxygen, and pH.
Hidayah, N. (Nurul), Rahmawati, D. (Dwi)
core   +3 more sources

Origin of salinity in a multilayered aquifer with high salinization vulnerability

Hydrological Processes, 2011
AbstractThe Kaluvelly watershed is a coastal area (Tamil Nadu, India) where water abstraction has resulted in a dramatic fall in the level of the water table and a piezometric depression in the most exploited aquifer, the Vanur aquifer. In addition, intensification/mechanization of agriculture may have affected the quality of recharge water. An initial
Gassama, Nathalie, Dia, Aline, Violette, Sophie   +2 more
openaire   +4 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Strategic Switching from Conventional Urea to Nano-Urea for Sustaining the Rice–Wheat Cropping System

Plants
In the face of declining crop yields, inefficient fertilizer usage, nutrient depletion, and limited water availability, the efficiency of conventional NPK fertilizers is a critical issue in India.
Ashwani Kumar, Parvender Sheoran, Sunita Devi, Naresh Kumar, Kapil Malik, Manu Rani, Arvind Kumar, Pooja Dhansu, Shruti Kaushik, Ajay Kumar Bhardwaj, Anita Mann, Rajender Kumar Yadav   +11 more
doaj   +1 more source

Impact of water deficit (salt and drought) stress on physiological, biochemical and yield attributes on wheat (Triticum aestivum) varieties

The Indian Journal of Agricultural Sciences, 2018
This investigation was carried out to assess the combined effect of salt stress and drought on physiological and biochemical traits in wheat (Triticum aestivum L.) varieties so as to deduce the probable mechanism of stress tolerance in these varieties ...
ASHWANI KUMAR, SURINDER KUMAR SHARMA, CHARU LATA, RITU DEVI, NEERAJ KULSHRESTHA, S L KRISHNAMURTHY, KAILASH SINGH, RAJENDER KUMAR YADAV   +7 more
doaj   +1 more source

Offsetting with Salinity Credits: An Alternative to Irrigation Zoning [PDF]

Irrigation induced salinity is a serious problem in many countries around the world. In Australia, this type of salinity is most pronounced in the valley of the River Murray in South Australia.
Ancev, Tihomir, Spencer, Thomas
core   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

A Methodological Approach for Assessing Soil Salinity Hazard in Irrigated Areas. Case Study: The rut Irrigation District, Colombia [PDF]

, 2015
Se desarrolló una metodología para la evaluación y mapeo de la amenaza de salinización de suelos en distritos de riego de Colombia, con base en la concentración y tipo de sales en el agua de riego.
Angulo Rojas, Paola Andrea, Echeverri Sánchez, Andrés, Pérez, Cristo Facundo, Urrutia Cobo, Norberto   +3 more
core   +2 more sources

Groundwater Salinization in France

Procedia Earth and Planetary Science, 2013
AbstractThe state, sources, and vectors of salinity in French aquifers are assessed through a GIS-based approach and a literature review of geochemical studies. Seawater intrusion is dominant in the insular context, but the most impacted water bodies are inland aquifers affected by WRI with Permian to Tertiary evaporites, mixing with primary and ...
Kloppmann, W., Bourhane, A., Schomburgk, S.   +2 more
openaire   +3 more sources