Results 51 to 60 of about 32,361 (297)

Water Flux and Reverse Salt Flux

open access: yes, 2018
Following the increase in the world population and the demand for economic development, the need for energy has increased day by day. Rapidly increasing global energy consumption is supplied mainly by fossil fuels bearing the risk of exhaustion with ...
Enver Guler   +8 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Distribution of intertidal macrobenthic assemblages in relation to environmental factors in the Tagus estuary, western Portugal

open access: yesScientia Marina, 2013
Fourteen intertidal sites from the eastern mid-region of the Tagus estuary were considered in order to study their macrobenthic assemblages in relation to environmental factors.
Anxo Conde   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CFD analysis of mass transfer in spacer-filled channels for reverse electrodialysis [PDF]

open access: yes, 2014
Reverse electrodialysis (RE) is a promising technology for electric power generation by converting the chemical potential difference of a salinity gradient, within a stack equipped by selective ion-exchange membranes. Concentration polarization phenomena
TAMBURINI, Alessandro   +4 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Flow Convergence Caused by a Salinity Minimum in a Tidal Channel

open access: yesSan Francisco Estuary and Watershed Science, 2006
Residence times of dissolved substances and sedimentation rates in tidal channels are affected by residual (tidally averaged) circulation patterns. One influence on these circulation patterns is the longitudinal density gradient.
John C. Warner   +3 more
doaj  

The power of salinity gradients: An Australian example [PDF]

open access: yesRenewable and Sustainable Energy Reviews, 2015
Abstract The development and exploitation of sustainable and environmentally friendly energy sources are required in order to resolve global energy shortages and to reduce the reliance of many countries on fossil fuel combustion. Salinity gradient energy has been considered a potential candidate for renewable energy due to the abundance of saline ...
Fernanda Helfer, Charles Lemckert
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Handbook discusses salinity gradient processes in desalination

open access: yes, 2018
A handbook that reviews current developments in salinity gradient processes in desalination – one of the most promising technologies to improve energy efficiency in desalination – has been produced by two chemical engineering academics at the UK's ...

core   +1 more source

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