Results 81 to 90 of about 5,144,139 (259)

Myo-inositol oxygenase: A key player in the battle of Pacific white shrimp (Penaeus vannamei) against low-salinity stress

Aquaculture Reports
Salinity is an important physicochemical parameter in the aquatic environment that has a profound impact on the physiological processes of aquatic animals. Therefore, strong salinity adaptability is crucial for the survival of aquatic animals.
Shengwei Lin, Yiting Wu, Zhihao Zhang, Xinchen Wang, Fenglu Han, Chang Xu, Erchao Li   +6 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

The effect of humic acid on growth, yield, and some physiological parameters of wheat under salinity stress [PDF]

فیزیولوژی محیطی گیاهی, 2020
Salinity is a major environmental stress, reducing growth and yield of a wide variety of crops all over the world. The present study assessed effects of humic acid and salinity stress on the growth and some physiological responses of wheat in a pot ...
Reza Sharifi Asl, Mahnaz Jasemi Manesh, Mohammad Mirzaie Haydari   +2 more
doaj  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Low salinity stress increases the risk of Vibrio parahaemolyticus infection and gut microbiota dysbiosis in Pacific white shrimp

BMC Microbiology
Background Extreme precipitation events often cause sudden drops in salinity, leading to disease outbreaks in shrimp aquaculture. Evidence suggests that environmental stress increases animal host susceptibility to pathogens.
Yi-Ting Chang, Wan-Ting Huang, Ping-Lun Wu, Ramya Kumar, Han-Ching Wang, Hsiao-Pei Lu   +5 more
doaj   +1 more source

Effect of alternating salinity stress on the gut microbiota of razor clam Sinonovacula constricta

Frontiers in Marine Science
IntroductionRazor clam (Sinonovacula constricta) is a bivalve of economic importance that widely resides in coastal and estuarine areas where salinity fluctuates rapidly.
Yi Yuan, Qunqun Jiang, Qinggang Xue, Qinggang Xue, Zhihua Lin, Zhihua Lin, Wenfang Dai, Wenfang Dai   +7 more
doaj   +1 more source

Evaluation of barley (Hordeum vulgare L.) genotypes for salinity tolerance under field conditions using the stress indices

Ain Shams Engineering Journal, 2018
Developing a suitable method for properly screening barley tolerance under salt stress is of great significance. Barley (an excellent model for the prediction of crop response to climate change) salt tolerance was investigated using stress tolerance ...
A. Jamshidi, H.R. Javanmard
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source