Results 71 to 80 of about 169,118 (334)
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Agriculture, 2019 Treated wastewater irrigation began two decades ago in the Salinas Valley of California and provides a unique opportunity to evaluate the long-term effects of this strategy on soil salinization.
Prudentia Zikalala +2 more
doaj +1 more source
Influence of sediment redox conditions on uranium mobilisation during saline intrusion [PDF]
, 2013 This research was funded by the Natural Environment Research Council (grant NE/C506799/1: Studentship NE/H527116/1).In the UK, several coastal nuclear sites have been identified as vulnerable to future sea level rise.
Blake, WH +3 more
core +2 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Conservation Agriculture for combating land degradation in Central Asia: a synthesis
AIMS Agriculture and Food, 2016 This manuscript reviews scientific findings on agricultural systems, associated land degradation and selected remedies such as Conservation Agricultural (CA) practices to counterbalance these.
J.P.A. Lamers +5 more
doaj +1 more source
Crop management in greenhouses: adapting the growth conditions to the plant needs or adapting the plant to the growth conditions? [PDF]
Strategies for improving greenhouse crop production should target both developing advanced technological systems and designing improved plants. Based on greenhouse experiments, crop models and biotechnological tools, this paper will discuss the ...
Marcelis, L.F.M., Pascale, S., De
core +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Treatment Project Design for Weakly Saline Water Bodies in Desert Parks and Practice
Renmin Zhujiang, 2022 The eutrophication control of a saline park water body in the Inner Mongolia Plateau is conducted by constructing a complete aquatic ecosystem.Acid-alkali adjustment of this water body is carried out to build aquatic plant and animal communities in the ...
FENG Yu +3 more
doaj
Intestinal ion regulation exhibits a daily rhythm in Gymnocypris przewalskii exposed to high saline and alkaline water [PDF]
, 2022 Fei Wang +8 more
openalex +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source