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A Bioluminescent Probe for Salivary Cortisol
Bioconjugate Chemistry, 2011Cortisol is a classical biomarker for the stress levels of human beings. We fabricated highly sensitive bioluminescent probes for salivary cortisol. The following strategies were contrived in the molecular design. Gaussia princeps luciferase (GLuc) was dissected into two fragments, between which an N-terminal-extended ligand binding domain of ...
Sung Bae, Kim +2 more
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Stress and salivary cortisol during pregnancy
Psychoneuroendocrinology, 2005The purpose of this study was to determine whether exposure to stressful life events was associated with changes in levels of circulating cortisol during pregnancy in a population of 603 pregnant women. The participating pregnant women filled out a questionnaire and collected a morning and evening sample of saliva in early pregnancy (median 14th ...
Obel, Carsten +5 more
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Salivary cortisol patterns in vital exhaustion
Journal of Psychosomatic Research, 2000The syndrome of vital exhaustion (VE), a risk indicator for myocardial infarction, is characterized by excessive fatigue, irritability, and demoralization. Dysregulation of the hypothalamic-pituitary-adrenocortical (HPA) axis is a potential pathogenic mechanism in fatigue syndromes, but little is known about HPA function in syndromal VE.We assessed ...
N A, Nicolson, R, van Diest
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Optimism, positive affectivity, and salivary cortisol
British Journal of Health Psychology, 2005Objectives. Research on stress and salivary cortisol has focused almost exclusively on the effects of negative psychological conditions or emotional states. Little attention has been drawn to the impact associated with positive psychological conditions, which have been shown recently to have significant ...
Chan, CLW +9 more
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Salivary Cortisol Testing in Children
Issues in Comprehensive Pediatric Nursing, 1997Biological markers can identify links between human biology and human behavior. Cortisol, a marker of hypothalamic-pituitary-adrenocortical axis function, is a useful measure in research. Newer technology involving the measurement of cortisol in saliva is being utilized in research studies.
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Long‐term stability of salivary cortisol
Scandinavian Journal of Clinical and Laboratory Investigation, 2005The measurement of salivary cortisol provides a simple, non-invasive, and stress-free measure frequently used in studies of the hypothalamic-pituitary-adrenal axis activity. In research projects, samples are often required to be stored for longer periods of time either because of the protocol of the project or because of lack of funding for analysis ...
Garde, A H, Hansen, Åse Marie
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SALIVARY CORTISOL HYPERSECRETION IN JUVENILE DEPRESSION
Journal of Child Psychology and Psychiatry, 1988Abstract Thirty depressed inpatients aged 7–16 yrs were compared for salivary hypercortisolism with a control group of 16 inpatients of mixed diagnosis matched for age and sex. Four cortisol samples were taken over a 48 hr period: 8 a.m. and 11 p.m.
D M, Foreman, I M, Goodyer
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Postpartum blues: Salivary cortisol and psychological factors
Journal of Psychosomatic Research, 1990The relationships between several psychological variables and salivary cortisol levels were investigated in 70 young mothers throughout the first five days following the delivery of a healthy baby. We hypothesized that postpartum blues is associated with ineffective coping strategies, high anxiety levels, and elevated salivary cortisol concentrations ...
Ehlert, Ulrike +4 more
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Suspense Increases Salivary Cortisol
1986The pathological relevance of endocrine responses to stressful experiences is purely understood. This present lack of knowledge can be partly attributed to methodological difficulties, e.g. taking blood samples under laboratory conditions and limits to obtain samples continuously and in sufficient amounts.
D. H. Hellhammer +3 more
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Salivary cortisol and psychosocial hazards at work
American Journal of Industrial Medicine, 2008AbstractBackgroundExperimental and clinical evidence suggest that stress can lead to ill‐health through the disregulation of the hypothalamic–pituitary–adrenal (HPA) axis. Studies to date have produced equivocal results likely due to different methodologies and failure to account for confounding factors.
MAINA G +3 more
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