In this review we extensively describe the main post-translational modifications that give rise to the multiple proteoforms characterized to date in the human salivary proteome and their potential role. Most of the data reported were obtained by our group in over twenty-five years of research carried out on human saliva mainly by applying a top-down ...
Irene Messana +14 more
openaire +4 more sources
Salivary proteomics of healthy dogs: An in depth catalog. [PDF]
To provide an in-depth catalog of the salivary proteome and endogenous peptidome of healthy dogs, evaluate proteins and peptides with antimicrobial properties, and compare the most common salivary proteins and peptides between different breed phylogeny ...
Sheila M F Torres +6 more
doaj +1 more source
Human Antibody Response to Dengue Vector Salivary Proteins: A Mini-Review
The widespread expansion of dengue is alarming. The challenges of vector control strategies warrants the implementation of alternative assessments to curb its invasion.
Siti Nur Anasuha Safie +5 more
semanticscholar +1 more source
A Peptide Domain of Bovine Milk Lactoferrin Inhibits the Interaction between Streptococcal Surface Protein Antigen and a Salivary Agglutinin Peptide Domain [PDF]
ABSTRACT The peptide domain of salivary agglutinin responsible for its interaction with cell surface protein antigen (PAc) of Streptococcus mutans or bovine lactoferrin was found in the same peptide, scavenger receptor cysteine-rich domain peptide 2 (SRCRP2).
Oho, T. +3 more
openaire +4 more sources
Background Early childhood caries is an urgent public health concern. The aim of this study was to investigate salivary proteomic biomarkers for the surveillance of changes in the high-risk status of early childhood caries.
Xinzhu Zhou +7 more
doaj +1 more source
Modulation of Streptococcus mutans Adherence to Hydroxyapatite by Engineered Salivary Peptides
Since the modification of the proteinaceous components of the Acquired Enamel Pellicle (AEP) could influence the adhesion of Streptococcus mutans, the most cariogenic bacteria, to dental surfaces, we assessed if engineered salivary peptides would affect ...
L. M. Marin +3 more
semanticscholar +1 more source
Antibody Responses Against Anopheles darlingi Immunogenic Peptides in Plasmodium Infected Humans
Introduction: Malaria is still an important vector-borne disease in the New World tropics. Despite the recent decline in malaria due to Plasmodium falciparum infection in Africa, a rise in Plasmodium infections has been detected in several low malaria ...
Berlin Londono-Renteria +13 more
doaj +1 more source
Inhibition of bovine platelets aggregation in response to Hyalomma anatolicum salivary gland proteins/peptides [PDF]
Aim: Ticks are obligate ectoparasites that have an impact on wide range of vertebrates and also act as a potential vector for the transmission of tropical theileriosis, babesiosis, etc., causing significant loss to livestock production worldwide.
Surbhi +4 more
doaj +1 more source
Specific metallo-protein interactions and antimicrobial activity in Histatin-5, an intrinsically disordered salivary peptide [PDF]
AbstractHistatin-5 (Hst-5) is an antimicrobial, salivary protein that is involved in the host defense system. Hst-5 has been proposed to bind functionally relevant zinc and copper but presents challenges in structural studies due to its disordered conformation in aqueous solution.
Tyler G. McCaslin +3 more
openaire +2 more sources
Tryptogalinin is a tick Kunitz serine protease inhibitor with a unique intrinsic disorder. [PDF]
A salivary proteome-transcriptome project on the hard tick Ixodes scapularis revealed that Kunitz peptides are the most abundant salivary proteins. Ticks use Kunitz peptides (among other salivary proteins) to combat host defense mechanisms and to obtain ...
James J Valdés +6 more
doaj +1 more source

