Results 71 to 80 of about 49,253 (320)

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source

Lactoferrin. A natural glycoprotein involved in iron and inflammatory homeostasis [PDF]

, 2017
Human lactoferrin (hLf), an iron-binding multifunctional cationic glycoprotein secreted by exocrine glands and by neutrophils, is a key element of host defenses.
Cutone, Antimo, Lepanto, Maria Stefania, Paesano, Rosalba, Rosa, Luigi, Valenti, Piera   +4 more
core   +2 more sources

Genome‐Wide Association Study Reveals Insect Genetics and Microbial Symbiont Effects on Susceptibility of Diaphorina citri to the Citrus Greening Pathogen, Candidatus Liberibacter Asiaticus

Advanced Science, EarlyView.
This study investigates the genetic and microbial factors influencing the susceptibility of Diaphorina citri to the citrus greening pathogen Candidatus Liberibacter asiaticus (CLas), employing a microbiome Genome Wide Association Study. The research identifies a key gene encoding an MFS‐type transporter contributing to CLas infectivity and abundance in
Kai Liu, Qingcui He, Zeyue Lin, Shixuan Huang, Zichun Zhong, Pingyang Zhu, Mengge Gao, Luyao Zhao, Han Jin, Guiting Wu, Gurr M. Geoff, Qunxin Han, Rui Pang   +12 more
wiley   +1 more source

Colorectal cancer and inflammatory bowel diseases share common salivary proteomic pathways

Scientific Reports
Inflammatory bowels diseases (IBD) are high risk conditions for colorectal cancer (CRC). The discovery of IBD and CRC noninvasive protein/peptide biomarkers using saliva and feces was the aim of this study involving 20 controls, 25 IBD (12 Crohn’s ...
Nicole Contran, Giorgio Arrigoni, Ilaria Battisti, Renata D’Incà, Imerio Angriman, Cinzia Franchin, Maria L. Scapellato, Andrea Padoan, Stefania Moz, Ada Aita, Edoardo Savarino, Greta Lorenzon, Fabiana Zingone, Gaya Spolverato, Salvatore Pucciarelli, Evelyn Nordi, Paola Galozzi, Daniela Basso   +17 more
doaj   +1 more source

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

Advanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou, Yao Xiao, Ziyue Xu, Chengyu Yang, Jiang Li, Ya Liu, Ping Yin   +6 more
wiley   +1 more source

Comparative salivary proteome of hepatitis B- and C-infected patients. [PDF]

PLoS ONE, 2014
Hepatitis B and C virus (HBV and HCV) infections are an important cause of cirrhosis and hepatocellular carcinoma. The natural history has a prominent latent phase, and infected patients may remain undiagnosed; this situation may lead to the continuing ...
Lorena Da Rós Gonçalves, Isabele Batista Campanhon, Romênia R Domingues, Adriana F Paes Leme, Márcia Regina Soares da Silva   +4 more
doaj   +1 more source

Proteins and peptides in parotid saliva of irradiated patients compared to that of healthy controls using SELDI-TOF-MS

BMC Research Notes, 2015
Radiotherapy to the head and neck area damages the salivary glands. As a consequence hyposalivation may occur, but also the protein composition of saliva may be affected possibly compromising oral health.
A. Laheij, C. Rasch, B. Brandt, J. D. de Soet, R. Schipper, A. Loof, E. Silletti, C. van Loveren   +7 more
semanticscholar   +1 more source

Programmed cell death 6 interacting protein (PDCD6IP) and Rabenosyn-5 (ZFYVE20) are potential urinary biomarkers for upper gastrointestinal cancer [PDF]

, 2015
PURPOSE: Cancer of the upper digestive tract (uGI) is a major contributor to cancer-related death worldwide. Due to a rise in occurrence, together with poor survival rates and a lack of diagnostic or prognostic clinical assays, there is a clear need ...
Adachi, Ballehaninna, Banks, Baron, Brennan, Caffrey, Chang, Chechlinska, Chung, Clemons, den Broek, Driemel, Ferlay, Fry, Gonzales, Gronn, Gungor, Guo, Hamm, Haren, Havanapan, Hennies, Honda, Hu, Hua, Husi, Jacobs, Jayapalan, Kentsis, Kim, Koomen, Lee, Lee, Lee, Lee, Li, Lyubimova, Makawita, Maliniemi, Matsumoto, McKiernan, Melle, Muley, Navaroli, Nicol, Pan, Passerini, Rastogi, Ren, Sanchez-Carbayo, Shah, Shahbaz Sarwar, Singh, Sofiadis, Song, Tanzer, Taylor, Toriola, Van, Villanueva, Wang, Wang, Wei, Winden, Xie, Zelvyte, Zhang, Zhang, Zhang   +68 more
core   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

Advanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu, Abudureyimujiang Aili, Zheng Kuang, Liting Cao, Zemin Li, Ying Shang, Yingying Ge, Tingting Hu, Yongchang Sun, Wuli Zhao, Rong Jin, Chun Chang   +11 more
wiley   +1 more source

Metaproteomics of saliva identifies human protein markers specific for individuals with periodontitis and dental caries compared to orally healthy controls [PDF]

PeerJ, 2016
Background The composition of the salivary microbiota has been reported to differentiate between patients with periodontitis, dental caries and orally healthy individuals.
Daniel Belstrøm, Rosa R. Jersie-Christensen, David Lyon, Christian Damgaard, Lars J. Jensen, Palle Holmstrup, Jesper V. Olsen   +6 more
doaj   +2 more sources