Results 21 to 30 of about 17,859 (212)

Relationship between FEV1 change and patient-reported outcomes in randomised trials of inhaled bronchodilators for stable COPD: a systematic review. [PDF]

, 2011
BACKGROUND: Interactions between spirometry and patient-reported outcomes in COPD are not well understood. This systematic review and study-level analysis investigated the relationship between changes in FEV1 and changes in health status with ...
Bourbeau, J, Capkun-Niggli, G, Cerulli, A, Jones, PW, Westwood, M, Worthy, G   +5 more
core   +2 more sources

Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease. [PDF]

, 2014
BACKGROUND: Inhaled corticosteroids (ICS) are anti-inflammatory drugs that have proven benefits for people with worsening symptoms of chronic obstructive pulmonary disease (COPD) and repeated exacerbations.
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core   +1 more source

Long-Acting β2 Adrenergic Receptor Agonist Ameliorates Imiquimod-Induced Psoriasis-Like Skin Lesion by Regulating Keratinocyte Proliferation and Apoptosis

Frontiers in Pharmacology, 2022
Psoriasis is a chronic inflammatory disease that affects approximately 1%–5% of the population worldwide. Considering frequent relapse, adverse drug reactions, and large costs of treatment, it is urgent to identify new medications for psoriasis ...
Rui Xu, Rui Xu, Shi Feng, Shi Feng, Zhou Ao, Zhou Ao, Yingxiang Chen, Yingxiang Chen, Congping Su, Congping Su, Xiuling Feng, Qin Fu, Qin Fu, Xiaoyan Yang, Xiaoyan Yang   +14 more
doaj   +1 more source

Cost-Effectiveness of Umeclidinium/Vilanterol versus Salmeterol/Fluticasone in Elderly Patients with Chronic Obstructive Pulmonary Diseases in China

International Journal of COPD, 2022
Ying Lan,1 Nan Yang,2 Yirong Wang,1 Yujie Yang,1 Min Xu,1 Qin He1 1Department of Pharmacy, The Third People’s Hospital of Chengdu, Chengdu, People’s Republic of China; 2West China School of Pharmacy, Sichuan University, Chengdu, People’s Republic of ...
Lan Y, Yang N, Wang Y, Yang Y, Xu M, He Q   +5 more
doaj  

Inhaled corticosteriod use and the risk of pneumonia and COPD exacerbations in the UPLIFT study [PDF]

, 2017
Rationale Unlike many other COPD studies, the 4-year UPLIFT trial permitted inhaled corticosteroid (ICS) use during run-in and treatment phases. This provided the opportunity to prospectively observe the continuing effects of ICS on respiratory events in
Morice, Alyn, Morice, Alyn H., Morjaria, Jaymin, Morjaria, Jaymin B., Rigby, Alan   +4 more
core   +1 more source

Economic Evaluation of Umeclidinium/Vilanterol versus Umeclidinium or Salmeterol in Symptomatic Non-Exacerbating Patients with COPD from a UK Perspective Using the GALAXY Model

International Journal of COPD, 2021
Soham Shukla,1 Dhvani Shah,2 Alan Martin,3 Nancy A Risebrough,4 Robyn Kendall,5 Claus F Vogelmeier,6 Isabelle Boucot,3 Lee Tombs,7 Leif Bjermer,8 Paul W Jones,3 Edward Kerwin,9 Chris Compton,3 François Maltais,10 David A Lipson,11,12 Afisi S Ismaila1,13 ...
Shukla S, Shah D, Martin A, Risebrough NA, Kendall R, Vogelmeier CF, Boucot I, Tombs L, Bjermer L, Jones PW, Kerwin E, Compton C, Maltais F, Lipson DA, Ismaila AS   +14 more
doaj  

Combination formoterol and budesonide as maintenance and reliever therapy versus combination inhaler maintenance for chronic asthma in adults and children. [PDF]

, 2013
BACKGROUND: Asthma is characterised by chronic inflammation of the airways and recurrent exacerbations with wheezing, chest tightness and cough. Treatment with inhaled steroids and bronchodilators often results in good control of symptoms, prevention of ...
Ferrara, G, Karner, C, Kew, KM, Mindus, SM   +3 more
core   +1 more source

Effects of Salmeterol Xinafoate and Fluticasone Propionate on Immunological Activation of Human Cultured Mast Cells

Allergology International, 2006
Background: The clinical efficacy of combination therapy comprising a long acting β2-agonist (LABA) and corticosteroid is widely recognized for the treatment of adult asthma.
Hirotomo Akabane, Masayuki Murata, Masafumi Kubota, Eiji Takashima, Hiroyuki Tanaka, Naoki Inagaki, Michiaki Horiba, Hiroichi Nagai   +7 more
doaj   +1 more source

Blood eosinophils and inhaled corticosteroid/long-acting β-2 agonist efficacy in COPD [PDF]

, 2015
Objective We performed a review of studies of fluticasone propionate (FP)/salmeterol (SAL) (combination inhaled corticosteroid (ICS)/long-acting β2-agonist (LABA)) in patients with COPD, which measured baseline (pretreatment) blood eosinophil levels, to ...
Barnes, NC, Jones, PW, Lettis, S, Locantore, N, Pascoe, S, Pavord, ID, Wedzicha, JA   +6 more
core   +1 more source

LABA/LAMA combinations versus LAMA monotherapy or LABA/ICS in COPD : a systematic review and meta-analysis [PDF]

, 2017
Acknowledgments The meta-analysis work was performed by Guruprasad Rao KS and Sharanbasappa Durg of Molecular Connections (P) Ltd, Bangalore, India, under the guidance of the manuscript authors and Novartis Pharma AG (Basel, Switzerland). Medical writing
Altman, Pablo, Anzueto, Antonio, Bader, Giovanni, Fogel, Robert, Kostikas, Konstantinos, Patalano, Francesco, Price, David B, Rodrigo, Gustavo J, Singh, Dave   +8 more
core   +2 more sources