Results 51 to 60 of about 10,206 (212)

Reduced suppressive effect of β2-adrenoceptor agonist on fibrocyte function in severe asthma

open access: yesRespiratory Research, 2017
Background Patients with severe asthma have increased airway remodelling and elevated numbers of circulating fibrocytes with enhanced myofibroblastic differentiation capacity, despite being treated with high doses of corticosteroids, and long acting β2 ...
Chun-Yu Lo   +7 more
doaj   +1 more source

Pleural Effusion Formation Linked to Altered Transporter Expression Involved in Alveolar Fluid Clearance: Insights From the Monocrotaline Model of Pulmonary Hypertension

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 137, Issue 4, October 2025.
ABSTRACT Pleural effusions (PLEF) in pulmonary arterial hypertension (PAH), particularly in patients with isolated right heart failure, are associated with poor prognosis and increased mortality. This study investigates changes in alveolar fluid clearance (AFC) transporter expression in relation to lung fluid accumulation and PLEF formation during PAH ...
Katarina Lelkova   +9 more
wiley   +1 more source

New developed spectrophotometric method for simultaneous determination of salmeterol xinafoate and fluticasone propionate in bulk powder and Seritide® diskus inhalation

open access: yesBulletin of Faculty of Pharmacy Cairo University, 2012
A new simple, accurate, precise, rapid and economical method was developed for the simultaneous determination of Salmeterol xinafoate and Fluticasone propionate in their binary mixture in bulk powder and Seritide diskus® inhalation.
Ahmed Samir   +2 more
doaj   +1 more source

Linezolid‐Associated Lactic Acidosis Triggering a Sepsis Alert: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 9, September 2025.
ABSTRACT Elevated lactate alone may trigger false sepsis alerts. In this case, linezolid‐induced lactic acidosis mimicked sepsis, triggering automated alerts. Clinicians should consider medication‐related causes of lactate elevation and apply clinical context in interpreting automated alerts to avoid unnecessary interventions, alert fatigue, and ...
Yusuf Kagzi, Moni Roy, Tulika Chatterjee
wiley   +1 more source

Uncovering the regional localization of inhaled salmeterol retention in the lung

open access: yesDrug Delivery, 2018
Treatment of respiratory disease with a drug delivered via inhalation is generally held as being beneficial as it provides direct access to the lung target site with a minimum systemic exposure.
Erica Bäckström   +7 more
doaj   +1 more source

Patient‐Reported Adverse Drug Events on Nirmatrelvir–Ritonavir: A Prospective Observational Study of a Pharmacist‐Led Follow‐Up and Monitoring Service

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 8, Issue 9, Page 842-849, September 2025.
ABSTRACT Background There is a paucity of population‐based data on adherence and adverse drug events (ADEs) associated with the treatment of coronavirus disease 2019 (COVID‐19) with nirmatrelvir and ritonavir (NMV/r). We sought to contribute data on patient‐reported treatment adherence and ADEs with NMV/r using data collected by community pharmacists ...
Colin R. Dormuth   +4 more
wiley   +1 more source

The comparative effectiveness of initiating fluticasone/salmeterol combination therapy via pMDI versus DPI in reducing exacerbations and treatment escalation in COPD: a UK database study

open access: yesInternational Journal of COPD, 2017
Rupert Jones,1 Jessica Martin,2 Vicky Thomas,3 Derek Skinner,4 Jonathan Marshall,5 Martina Stagno d’Alcontres,2 David Price2,6 1Clinical Trials and Health Research, Institute of Translational and Stratified Medicine, Plymouth University Peninsula ...
Jones R   +6 more
doaj  

Effect of Fluticasone and Salmeterol on Tracheal Responsiveness to Ovalbumin and Lung Inflammation, Administrated during and after Sensitization

open access: yesThe Scientific World Journal, 2014
The effect of duration of administration of fluticasone propionate and salmeterol on tracheal responsiveness to ovalbumin and total and differential white blood cell in sensitized guinea pig was examined.
Zahra Gholamnezhad   +4 more
doaj   +1 more source

EFFECT OF BRONCHODILATORS ON HEART RATE VARIABILITY IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

open access: yesРациональная фармакотерапия в кардиологии, 2015
Aim. To study effect of long-acting theophylline (Theotard, KRKA) and combination of salmeterol and fluticasone (Seretide, GlaxoSmithKline) on heart rhythm variability (HRV) and number of arrhythmic episodes in patients with chronic obstructive pulmonary
H. H. Shugushev   +2 more
doaj   +1 more source

Low-dose Fluticasone Propionate in Combination With Salmeterol in Patients With Chronic Obstructive Pulmonary Disease

open access: yesClinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2018
Inhaled corticosteroids are widely used in the treatment of chronic obstructive pulmonary disease (COPD). However, their use has been questioned for appropriate dose and a possible increased risk of pneumonia. Here, we reviewed patients with COPD who had
Hideki Yasui   +16 more
doaj   +1 more source

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