Results 161 to 170 of about 1,963 (217)

Mixed-type Dyspnoea Diagnosed via Non-invasive and Invasive Cardiopulmonary Exercise Tests. [PDF]

open access: yesIntern Med
Takamura Y   +11 more
europepmc   +1 more source

Nanoparticles to target asthma.

open access: yesAm J Physiol Lung Cell Mol Physiol
Hamrick SK   +4 more
europepmc   +1 more source

Solubility prediction of salmeterol xinafoate in water–dioxane mixtures

International Journal of Pharmaceutics, 2001
The mole fraction solubility of salmeterol xinafoate was determined in various concentrations of dioxane in aqueous binary mixture. Maximum solubility was observed in 90% v/v dioxane and solubility parameter of the solute was estimated from solubility peak equal to 24.99 MPa(0.5).
A, Jouyban-Gharamaleki   +3 more
openaire   +4 more sources

Salmeterol Xinafoate (SX) loaded into mucoadhesive solid lipid microparticles for COPD treatment

International Journal of Pharmaceutics, 2019
Chronic obstructive pulmonary disease (COPD) is one of the main health problems worldwide. It is characterised by chronic inflammation in the lungs that leads to progressive, chronic, largely irreversible airflow obstruction. The use of long-acting β agonists remain today the frontline treatment for COPD with the aim of minimizing side effects and ...
Erika Amore   +9 more
openaire   +6 more sources

Effect of carrier size on the dispersion of salmeterol xinafoate from interactive mixtures

Journal of Pharmaceutical Sciences, 2004
The objective of this study was to determine the influence of lactose carrier size on drug dispersion of salmeterol xinafoate (SX) from interactive mixtures. SX dispersion was measured by using the fine particle fractions determined by a twin stage impinger attached to a Rotahaler. The particle size of the lactose carrier in the SX interactive mixtures
Islam, Nazrul   +3 more
openaire   +5 more sources

Adhesion and redistribution of salmeterol xinafoate particles in sugar-based mixtures for inhalation

International Journal of Pharmaceutics, 2007
The aim of this study was to evaluate coarse and fine sugars as potential alternative excipients in dry powder inhalation formulations and to develop a greater understanding of the key interactions between the particulate species in these mixtures. Interactive mixtures composed of salmeterol xinafoate (SX) and different type of sugars (lactose, glucose,
Handoko, Adi   +2 more
openaire   +4 more sources

Salmeterol xinafoate as maintenance therapy compared with albuterol in patients with asthma.

JAMA, 1994
To compare the efficacy and safety of inhaled salmeterol xinafoate, a long-acting beta 2-adrenoceptor agonist, with that of albuterol, a short-acting inhaled beta 2-agonist, in the treatment of asthma.Randomized, double-blind, placebo-controlled, parallel-group study.Eleven outpatient clinical centers.A total of 322 male and female patients at least 12
G E, D'Alonzo   +5 more
openaire   +3 more sources

Salmeterol Xinafoate

2015
Salmeterol xinafoate is a potent and a long-acting β2-adrenoceptor agonist. It is prescribed for the treatment of severe persistent asthma and chronic obstructive pulmonary disease. Different methods were used to prepare (R)-(-)-salmeterol such as: mixing a sample of 4-benzyloxy-3-hydroxymethyl-ω-bromoacetophenone with sodium lauryl sulfate and the ...
Manal M, Anwar   +2 more
openaire   +2 more sources

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