Results 21 to 30 of about 1,963 (217)

Development of Novel Fluticasone/Salmeterol/Tiotropium-Loaded Dry Powder Inhaler and Bioequivalence Assessment to Commercial Products in Rats [PDF]

Pharmaceutics
Background/Objectives: Inhaler devices have been developed for the effective delivery of inhaled medications used in the treatment of pulmonary diseases.
Hyukjun Cho, Hyunji Lee, Duhyeong Hwang
doaj   +2 more sources

Salmeterol xinafoate: an analysis of outcomes and cost-effectiveness using a primary care database

Respiratory Medicine, 1998
Long-acting inhaled /&-agonists (LABS), used in conjunction with low-dose inhaled steroids, are a recommended alternative to high-dose inhaled steroids for asthmatics with persistent symptoms (1). There are, however, few published data regarding their cost-effectiveness.
David Price, K. Cargill, Stephanie Wolfe, H. Darby   +3 more
openalex   +3 more sources

Determination of salmeterol xinafoate and its degradation products according to ICH guidelines with use of UPLC technique [PDF]

, 2011
The objective of reducing analysis time and maintaining good efficiency, there has been substantial focus on high-speed chromatographic separations. Recently, commercially available ultra performance liquid chromatography (UPLC) has proven to be one of ...
Karthikeyan, Chandrabose, Moorthy, N.S.H.N., Patel, Pratibha, Sahu, Kapendra, Trivedi, Piyush   +4 more
core   +2 more sources

Cost-Effectiveness Analysis of Treatments for Children With Uncontrolled Asthma Symptoms Despite Inhaled Corticosteroids. [PDF]

Pediatr Pulmonol
ABSTRACT Introduction There is uncertainty about the cost‐effectiveness of treatment options for children and adolescents with uncontrolled asthma despite inhaled corticosteroid (ICS) treatment. Methods A Markov state‐transition model was developed to simulate costs from the perspective of the National Health Service in the UK and health outcomes ...
Culeddu G, Cividini S, Sinha I, Donegan S, Rose K, Fulton O, Turner S, Smith CT, Hughes DA, EINSTEIN collaborative group.   +9 more
europepmc   +2 more sources

Preliminary Assessment of Tc-Salmeterol Xinafoate as a Potential Bone Imaging Agent [PDF]

The Open Conference Proceedings Journal, 2016
Wafaa A. Zaghary, M. A. Motaleb, Manal M. Anwar   +2 more
openalex   +2 more sources

Impact of Mechanistic Modeling and Simulation Methodologies on Product-Specific Guidance Development for Non-Orally Administered Drug Products. [PDF]

CPT Pharmacometrics Syst Pharmacol
ABSTRACT The U.S. Food and Drug Administration (FDA) publishes product‐specific guidances (PSGs), with bioequivalence (BE) recommendations for prospective generics. Developing BE recommendations for non‐orally administered drug products including long‐acting injectables (LAI), orally inhaled drug products, and drugs applied locally to the skin ...
Chopski SG, Walenga RL, Tan ML, Alam K, Babiskin A, Fang L, Tsakalozou E.   +6 more
europepmc   +2 more sources

Treatment adherence and level of control in moderate persistent asthma in children and adolescents treated with fluticasone and salmeterol

Jornal de Pediatria, 2019
Objective: There is a scarcity of studies that assessed the association between adherence to combination therapy and asthma control in pediatric patients.
Nulma S. Jentzsch, Gabriela C.G. Silva, Guilherme M.S. Mendes, Paul L.P. Brand, Paulo Camargos   +4 more
doaj   +3 more sources

A mariner's tale: Invasive endotracheal Mycobacterium marinum infection

Respirology Case Reports, Volume 11, Issue 10, October 2023., 2023
In humans, Mycobacterium marinum infections are acquired through direct inoculation of skin wounds and are almost exclusively localized to skin and soft tissues. Pulmonary infection with M. marinum is extremely rare, and to our knowledge, invasive endobronchial disease has not been reported previously.
Peter T. Bell, James Anderson, Christopher Coulter, Andrew J. Dettrick, Andrew Burke, Timothy Baird   +5 more
wiley   +1 more source

Mechanistic modeling of generic orally inhaled drug products: A workshop summary report

CPT: Pharmacometrics &Systems Pharmacology, Volume 12, Issue 5, Page 560-574, May 2023., 2023
Abstract In silico mechanistic modeling approaches have been designed by various stakeholders with the goal of supporting development and approval of generic orally inhaled drug products in the United States. This review summarizes the presentations and panel discussion that comprised a workshop session concentrated on the use of in silico models to ...
Ross L. Walenga, Clare Butler, Brent A. Craven, P. Worth Longest, Raja Mohamed, Bryan Newman, Bo Olsson, Günther Hochhaus, Bing V. Li, Markham C. Luke, Liang Zhao, Andrzej Przekwas, Robert Lionberger   +12 more
wiley   +1 more source

Cardiac impact of inhaled therapy in the largest randomised placebo-controlled trial in COPD history [PDF]

, 2016
SUMMIT supports the efficiency and cardiovascular safety of LABA and ICS in COPD patients at cardiovascular risk http://ow.ly ...
Andreas, S. (Stefan), Janson, C. (Christer), Lahousse, L. (Lies), Van Den Berge, M. (Maarten)   +3 more
core   +15 more sources