Results 241 to 250 of about 751,049 (351)

Development and adoption of Kernza—A perennial grain crop for sustainable agriculture

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Annual cereal grains account for ~50% of human food calories, but cultivation of these crops has resulted in major environmental and social issues worldwide. For nearly three decades, researchers have been breeding intermediate wheatgrass—a perennial cool‐season grass—to serve as the world's first commercial‐scale perennial grain crop to improve ...
Jessica L. Gutknecht   +15 more
wiley   +1 more source

Interplay of Ser273 Phosphorylation and K268 and K293 Acetylation in PPARγ: Implications for PPARγ Activation

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) play a critical role in regulating the transcriptional activity of PPARγ, a nuclear receptor central to glucose and lipid homeostasis. Among these, lysine acetylation at K268 and K293 and phosphorylation at S273 are particularly relevant to insulin sensitivity.
Caique Camargo Malospirito   +6 more
wiley   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

Engineered Gravel Trench Hyporheic Exchange to Create Cold‐Water Thermal Refuges

open access: yesRiver Research and Applications, EarlyView.
ABSTRACT Warming rivers are driving a loss or fragmentation of cold‐water habitat and providing the impetus to develop proactive thermal management approaches to maintain suitable habitat in rivers. One innovative approach is through the creation of cold‐water thermal refuges during periods of thermal stress for aquatic species.
Kathryn A. Smith   +3 more
wiley   +1 more source

A Tool for Prioritizing Gravel Augmentation Reaches for Sediment Starved Rivers

open access: yesRiver Research and Applications, EarlyView.
ABSTRACT Gravel augmentation is a widely used restoration technique used to improve habitat below dams, including salmonids spawning habitat. However, gravel augmentation can be cost‐prohibitive, and it is often unclear which stream segments have the highest potential to benefit spawning salmonids.
Patricia J. Wohner   +2 more
wiley   +1 more source

Linking aerobic scope to fitness in the wild reveals potential opportunities to help recover imperiled salmon populations. [PDF]

open access: yesCommun Biol
Burford BP   +8 more
europepmc   +1 more source

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