Results 121 to 130 of about 531,417 (343)
Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu +16 more
wiley +1 more source
Akikazu Sakudo,1,2 Risa Yamashiro,2 Makoto Haritani,3 Koichi Furusaki,4 Rumiko Onishi,5 Takashi Onodera3 1Faculty of Veterinary Medicine, Okayama University of Science, Imabari, Ehime 794-8555, Japan; 2Laboratory of Biometabolic Chemistry, School of ...
Sakudo A +5 more
doaj
ABSTRACT Antimicrobial resistance is an increasing threat to public health, with alarming estimates of mortality rates. In this context, the clinical properties of Varronia curassavica Jacq. are highlighted due to its biological and pharmacological activities.
José Thyálisson da Costa Silva +18 more
wiley +1 more source
In vivo and in silico toxicological effects of Calea phyllolepis extracts Standardized on 6‐epi‐β‐Verbesinol Coumarate. ABSTRACT Medicinal plants are traditionally used in folk medicine. Still, there is a misconception about the safety/efficacy of natural treatments, which results in few studies on the toxic, genotoxic, and mutagenic potential of ...
Suele Bierhals Vencato +6 more
wiley +1 more source
Agrimony is a medicinal herb known for its content of polyphenols and beneficial bioactivity, both of which can be strongly influenced by cultivation and processing. This study reveals that agrimony plant structures, species, and postharvest processing are the main drivers of observed variability in both phytochemical composition and antimicrobial ...
Anna Loučková +7 more
wiley +1 more source
Antimicrobial Activity and Chemical Constituents of Siparuna guianensis (Siparunaceae)
ABSTRACT Siparuna guianensis (Siparunaceae) is an Amazonian plant known by the popular name of Negramina. There are several reports of the use of this plant in folk medicine. In the present work, we decided to study its extracts, aiming at the isolation of compounds and verifying their antimicrobial activities.
Olência Mento Manuensa Vilanculo +7 more
wiley +1 more source
ABSTRACT Cyanobacteria are photosynthetic microorganisms known for producing diverse bioactive compounds. This study explores the bioactivity of extracts and fractions from Amazonian cyanobacteria and their pigment and phenolic compound production. A fraction from Synechococcus sp. CACIAM 05 showed cytotoxicity against hCMEC/D3 and MG‐63 cells.
Samuel Cavalcante do Amaral +8 more
wiley +1 more source
ABSTRACT The chemical composition of 66 oil samples isolated from the berries of individual trees of Juniperus phoenicea var. turbinata, collected in six locations from Algeria, was investigated by gas chromatography with flame ionization detection, gas chromatography‐mass spectrometry, and 13C‐nuclear magnetic resonance.
Chérifa Yassamine Osmani +6 more
wiley +1 more source

