Results 81 to 90 of about 112,007 (195)

Fluorescent Antibiotics: Bridging Diagnostic and Therapy in the Fight against Bacterial Infections

Small Science, EarlyView.
This review critically evaluates fluorescent antibiotics as promising agents combining diagnostic precision with therapeutic efficacy. It highlights advances in probe design, chemical conjugation strategies, real‐time imaging applications, selective pathogen detection, and targeted therapy. The potential to combat antimicrobial resistance is discussed,
Tan Phuoc Ton, Richard Bright, Vi Khanh Truong, Krasimir Vasilev   +3 more
wiley   +1 more source

Multiresistant Salmonella enterica serovar 4,[5],12:i:- in Europe: a new pandemic strain? [PDF]

, 2010
A marked increase in the prevalence of S. enterica serovar 4,[5],12:i:- with resistance to ampicillin, streptomycin, sulphonamides and tetracyclines (R-type ASSuT) has been noted in food-borne infections and in pigs/pig meat in several European countries
Granier, A., Guerra, B., Hopkins, K.L., Jakubczak, A., Kirchner, M., Lucarelli, C., Mevius, D.J., Porrero, M.C., Threlfall, J.   +8 more
core   +3 more sources

Systems Biology and Pangenome of Salmonella O-Antigens. [PDF]

, 2019
O-antigens are glycopolymers in lipopolysaccharides expressed on the cell surface of Gram-negative bacteria. Variability in the O-antigen structure constitutes the basis for the establishment of the serotyping schema. We pursued a two-pronged approach to
Kavvas, Erol, Machado, Henrique, Monk, Jonathan M, Palsson, Bernhard O, Seif, Yara   +4 more
core   +2 more sources

A Chemogenetic Toolkit for Inducible, Cell Type‐Specific Actin Disassembly

Small Methods, EarlyView.
ChiActs are novel actin‐perturbing genetic tools that can be rapidly activated by chemical actuators and optogenetically targeted to distinct subcellular locations using light. ChiActs rapidly induce actin disassembly in several model cell types and are able to perturb actin‐dependent nano‐assembly and cellular functions, including inhibition of ...
Tien‐Hung Lan, Nicholas Ambiel, Yi‐Tsang Lee, Tatsuki Nonomura, Yubin Zhou, J. Bradley Zuchero   +5 more
wiley   +1 more source

Gut Microbiota as a Mediator Between Intestinal Fibrosis and Creeping Fat in Crohn's Disease

United European Gastroenterology Journal, EarlyView.
ABSTRACT Intestinal stricture remains one of the most challenging complications in Crohn's disease, and its underlying mechanisms are poorly understood. Accumulating evidence suggests that gut microbiota is significantly altered in stenotic intestines and may play a key role in the development of fibrogenesis in Crohn's disease.
Caiguang Liu, Rongchang Li, Jing Nie, Jinshen He, Zihao Lin, Xiaomin Wu, Jinyu Tan, Zishan Liu, Longyuan Zhou, Xiaozhi Li, Zhirong Zeng, Minhu Chen, Shixian Hu, Yijun Zhu, Ren Mao   +14 more
wiley   +1 more source

Salmonella enterica Serovar Typhimurium 14028s Genomic Regions Required for Colonization of Lettuce Leaves. [PDF]

, 2020
Contamination of edible produce leaves with human bacterial pathogens has been associated with serious disease outbreaks and has become a major public health concern affecting all aspects of the market, from farmers to consumers.
McClelland, Michael, Melotto, Maeli, Montano, Jeanine, Porwollik, Steffen, Rossidivito, Gabrielle, Sela Saldinger, Shlomo, Torreano, Joseph   +6 more
core  

The prevalences of Salmonella Genomic Island 1 variants in human and animal Salmonella Typhimurium DT104 are distinguishable using a Bayesian approach [PDF]

, 2011
Throughout the 1990s, there was an epidemic of multidrug resistant Salmonella Typhimurium DT104 in both animals and humans in Scotland. The use of antimicrobials in agriculture is often cited as a major source of antimicrobial resistance in pathogenic ...
Alison E. Mather, Daniel T. Haydon, Derek J. Brown, Dominic J. Mellor, John E. Coia, Louise Matthews, Maciej F. Boni, Matthew J. Denwood, Stuart W. J. Reid   +8 more
core   +3 more sources

An Atypical Kappa‐Class Chaperone‐Usher Fimbriae of a Human Enterotoxigenic Escherichia coli Strain Shows Multi‐Host Adherence and Distinct Phylogenetic Feature

Microbiology and Immunology, Volume 69, Issue 5, Page 270-279, May 2025.
ABSTRACT The pathogenesis of enterotoxigenic Escherichia coli (ETEC) involves the colonization of hosts by colonization factors (CFs) and the secretion of enterotoxins. CFs, especially chaperone‐usher fimbriae, mediate bacterial adhesion to host cells, with extensive genetic diversity observed among isolates.
Hiharu Inoue, Yoshihiko Tanimoto, Dongming Zheng, Erika Ban‐Furukawa, Miyoko Inoue, Yuko Omori, Yoshihiro Yamaguchi, Taro Tachibana, Hisashi Aso, Weiping Zhang, Eriko Kage‐Nakadai, Yoshikazu Nishikawa, Takayuki Wada   +12 more
wiley   +1 more source

Ceftazidime-ResistantSalmonella enterica, Morocco

Emerging Infectious Diseases, 2009
إلى المحرر: شكراً جزيلاً على قسمك الخاص المثير للاهتمام والمفيد حول الأمراض المعدية في منطقة الأمازون (1). يجب أن يكون قراؤك مهتمين أيضًا ببرنامج صحي مستدام معروف قليلاً، ولكنه ناجح للغاية، بدأ في الأمازون. في عام 1942، وافقت حكومتا البرازيل والولايات المتحدة على إنشاء خدمة خاصة للصحة العامة (تسمى Serviço Especial de Saúde Pública).
Brahim Bouchrif, Simon Le Hello, Maria Pardos, Bouchra Karraouan, Jean-David Perrier-Gros-Claude, Moulay Mustapha Ennaji, Mohammed Timinouni, François‐Xavier Weill   +7 more
openaire   +5 more sources

Klebsiella pneumoniae contributes to altered cytotoxicity of thiopurines in vitro: Possible implications of biotransformation and bacterial metabolism

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose Thiopurines are used in paediatric inflammatory bowel disease (IBD), but some patients do not respond. Because the gut microbiota influences drug efficacy and IBD‐patient microbiota presents increased bacterial abundance, we investigated the impact of candidate Enterobacteriaceae on drug cytotoxicity, metabolism and ...
Martina Franzin, Cristina Lagatolla, Sofia Sindici Forgiarini, Mathias Haag, Sylvia Karin Neef, Manola Comar, Elke Schaeffeler, Barbara Bellich, Matteo Bramuzzo, Giuliana Decorti, Marianna Lucafò, Ute Hofmann, Matthias Schwab, Gabriele Stocco   +13 more
wiley   +1 more source