Molecular insights into farm animal and zoonoticSalmonellainfections [PDF]
Salmonella entericais a facultative intracellular pathogen of worldwide importance. Infections may present in a variety of ways, from asymptomatic colonization to inflammatory diarrhoea or typhoid fever depending on serovar- and host-specific factors. Human diarrhoeal infections are frequently acquiredviathe food chain and farm environment by virtue of
Stevens, Mark P. +2 more
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The prevalences of Salmonella Genomic Island 1 variants in human and animal Salmonella Typhimurium DT104 are distinguishable using a Bayesian approach [PDF]
Throughout the 1990s, there was an epidemic of multidrug resistant Salmonella Typhimurium DT104 in both animals and humans in Scotland. The use of antimicrobials in agriculture is often cited as a major source of antimicrobial resistance in pathogenic ...
Matthew J Denwood +38 more
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Target identification for prevention and therapy of "Salmonella" infections [PDF]
In this thesis we investigated maintenance requirements of Salmonella during chronic infections, and determined the relevant antigen properties that might facilitate the development of Salmonella vaccines. Overall, we wanted to achieve two goals: a)To
Barat, Somedutta
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Salmonella transiently reside in luminal neutrophils in the inflamed gut. [PDF]
Enteric pathogens need to grow efficiently in the gut lumen in order to cause disease and ensure transmission. The interior of the gut forms a complex environment comprising the mucosal surface area and the inner gut lumen with epithelial cell debris and
Mathias Heikenwalder (79126) +40 more
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Conservation of Salmonella Infection Mechanisms in Plants and Animals
Salmonella virulence in animals depends on effectors injected by Type III Secretion Systems (T3SSs). In this report we demonstrate that Salmonella mutants that are unable to deliver effectors are also compromised in infection of Arabidopsis thaliana plants.
Schikora, Adam +10 more
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Salmonella infection in calves and other animals [PDF]
Abstract In a 2 1/2‐year survey of salmonella infection in animals being slaughtered at meat works, approximately 5% of 7,497 samples, from 2,755 animals, and the pasture and water supply of five farms, were found to contain salmonellae. The predominant type was S. typhimurium
P. M. Nottingham, A. J. Urselmann
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A quantitative analysis of Salmonella Typhimurium metabolism during infection [PDF]
In this thesis, Salmonella metabolism during infection was investigated. The goal was to gain a quantitative and comprehensive understanding of Salmonella in vivo nutrient supply, utilization and growth.
Steeb, Benjamin
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Salmonella infection in calves and other animals [PDF]
Abstract In a further study of salmonella infection in animals being slaughtered at meatworks, 6.6% of 1,357 calves and 9.9% of 876 pigs were found to have salmonellae in one or more of the faeces or tissue samples examined.
P.M. Nottingham, N. Penney, R. Wyborn
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Salmonella Typhi and Salmonella Paratyphi A elaborate distinct systemic metabolite signatures during enteric fever. [PDF]
The host-pathogen interactions induced by Salmonella Typhi and Salmonella Paratyphi A during enteric fever are poorly understood. This knowledge gap, and the human restricted nature of these bacteria, limit our understanding of the disease and impede the
Thanh, TH +47 more
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Spatial and spatio-temporal analysis of Salmonella infection in dairy herds in England and Wales [PDF]
Using data from a cohort study conducted by the Veterinary Laboratories Agency (VLA), evidence of spatial clustering at distances up to 30 kin was found for S. Agama and S.
Fenton, S +13 more
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