Results 41 to 50 of about 125,644 (316)

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Salmonella Infection in Chronic Inflammation and Gastrointestinal Cancer

Diseases, 2019
Salmonella not only causes acute infections, but can also cause patients to become chronic “asymptomatic” carriers. Salmonella has been verified as a pathogenic factor that contributes to chronic inflammation and carcinogenesis.
Lang Zha, Shari Garrett, Jun Sun
doaj   +1 more source

Chronic effects of a Salmonella type III secretion effector protein AvrA in vivo. [PDF]

PLoS ONE, 2010
Salmonella infection is a common public health problem that can become chronic and increase the risk of inflammatory bowel diseases and cancer. AvrA is a Salmonella bacterial type III secretion effector protein. Increasing evidence demonstrates that AvrA
Rong Lu, Shaoping Wu, Xingyin Liu, Yinglin Xia, Yong-Guo Zhang, Jun Sun   +5 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Toward Molecular Level of the “Salmonella-Victim” Ecology, Genetics, and Evolution

The Scientific World Journal, 2004
Bacteria of the Salmonella genus are polypathogenic agents that can affect both men and animals, causing devastating and fatal illness. Despite considerable immunological, epidemiological, and genetic efforts, and increased understanding of how the ...
S.N. Rumyantsev
doaj   +1 more source

Selected lactic acid-producing bacterial isolates with the capacity to reduce Salmonella translocation and virulence gene expression in chickens. [PDF]

PLoS ONE, 2014
BACKGROUND:Probiotics have been used to control Salmonella colonization/infection in chickens. Yet the mechanisms of probiotic effects are not fully understood.
Xiaojian Yang, Jennifer Brisbin, Hai Yu, Qi Wang, Fugui Yin, Yonggang Zhang, Parviz Sabour, Shayan Sharif, Joshua Gong   +8 more
doaj   +1 more source

Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim, Hwi Won Seo, Kyuri Lee, Dongeun Yong, Yoon Kyung Park, Yujin Lee, Solip Lee, Do‐Wan Kim, Dajeong Kim, Choong‐Min Ryu   +9 more
wiley   +1 more source

Phage-resistance alters Lipid A reactogenicity: a new strategy for LPS-based conjugate vaccines against Salmonella Rissen

Frontiers in Immunology
Salmonella enterica serovar Rissen (S. Rissen) is an emerging causative agent of foodborne diseases. The current emergence of antibiotic resistance makes necessary alternative therapeutic strategies.
Paola Cuomo, Paola Cuomo, Chiara Medaglia, Angela Casillo, Antonio Gentile, Antonio Gentile, Carmine Fruggiero, Maria Michela Corsaro, Rosanna Capparelli, Rosanna Capparelli   +9 more
doaj   +1 more source

Pathological study of alcoholic plant agolanceolata crude extracts effect on some Salmonella species invitro and in vivo

Kufa Journal for Veterinary Medical Sciences, 2016
This study was designed to explore the pathological effect of alcoholic plant agolanceolata crude extracts effect on some Salmonella species invitro and in vivo study by using laboratory mice .plant agolanceolata  crude extract were dealing in vitro ...
Narjis Amer AL-kafaji, Zainab R. Zghair, MethaqGhlibAbd AL-Rubaie   +2 more
doaj   +1 more source