Results 61 to 70 of about 3,422,852 (337)

NLRP3 recruitment by NLRC4 during Salmonella infection

Journal of Experimental Medicine, 2016
By engineering a mutant mouse strain that preserves the scaffolding function of NLRC4, Dixit et al. show cooperativity between it and another NOD family sensor, NLRP3.
Yan Qu, S. Misaghi, K. Newton, Allie Maltzman, A. Izrael‐Tomasevic, D. Arnott, V. Dixit   +6 more
semanticscholar   +1 more source

Machine‐Learning‐Aided Advanced Electrochemical Biosensors

Advanced Materials, EarlyView.
Electrochemical biosensors are highly sensitive, portable, and versatile. Advanced nanomaterials enhance their performance, while machine learning (ML) improves data analysis, minimizes interference, and optimizes sensor design. Despite progress in both fields, their combined potential in diagnostics remains underexplored.
Andrei Bocan, Roozbeh Siavash Moakhar, Carolina del Real Mata, Max Petkun, Tristan De Iure‐Grimmel, Sripadh Guptha Yedire, Hamed Shieh, Arash Khorrami Jahromi, Sahar Sadat Mahshid, Sara Mahshid   +9 more
wiley   +1 more source

Exploiting neonatal host-bifidobacteria interactions to promote intestinal pathogen tolerance and barrier function: Bifidobacterium longum subsp. infantis outperforms Bifidobacterium adolescentis in anti-Salmonella activity and maintenance of intestinal homeostasis

Food Science and Human Wellness
Bifidobacterium longum subsp. infantis and Bifidobacterium adolescentis play important roles in the guts of infants and adolescents, respectively. In this study, using a neonatal rat model, we compared the protective effects of these 2 bifidobacterial ...
Chunxiu Lin, Shunhe Wang, Min Guo, Wentian Li, Jiayin Qiu, Yonghua Zhou, Hao Zhang, Wei Chen, Gang Wang   +8 more
doaj   +1 more source

Zebrafish Larvae as an in vivo Model for Antimicrobial Activity Tests against Intracellular Salmonella

Frontiers in Bioscience-Landmark, 2023
Introduction: Blood infections from multi-drug-resistant Salmonella pose a major health burden. This is especially true because Salmonella can survive and replicate intracellularly, and the development of new treatment strategies is dependent on ...
Patrick Hauswirth, Jonas Buck, Ramya Puligilla, Claudio Luca Alter, Sandro Sieber, Beatrice Claudi, Joseph Fanous, Dirk Bumann, Jörg Huwyler   +8 more
doaj   +1 more source

The Role of Artificial Intelligence in Advancing Biosensor Technology: Past, Present, and Future Perspectives

Advanced Materials, EarlyView.
This review explores the transformative role of AI in biosensor technology and provides a holistic interdisciplinary perspective that covers a broader scope of AI‐enabled biosensor technologies across various sectors including healthcare, environmental monitoring, food safety, and agriculture. It also highlights the important role of novel materials in
Tuğba Akkaş, Mahshid Reshadsedghi, Mustafa Şen, Volkan Kılıç, Nesrin Horzum   +4 more
wiley   +1 more source

Loss of NR2F6 Protects from Salmonella Typhimurium Infection

Advanced Science, EarlyView.
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk, Christa Pfeifhofer‐Obermair, Julia Benz, Natascha Brigo, Milena Bamberger, Alexeja Kleiter, Martin Hermann, Guenter Weiss, Natascha Hermann‐Kleiter   +8 more
wiley   +1 more source

Iron- and Hepcidin-Independent Downregulation of the Iron Exporter Ferroportin in Macrophages during Salmonella Infection

Frontiers in Immunology, 2017
Retention of iron in tissue macrophages via upregulation of hepcidin (HAMP) and downregulation of the iron exporter ferroportin (FPN) is thought to participate in the establishment of anemia of inflammation after infection.
A. Willemetz, S. Beatty, E. Richer, Aude Rubio, A. Auriac, R. Milkereit, O. Thibaudeau, S. Vaulont, D. Malo, F. Canonne-Hergaux   +9 more
semanticscholar   +1 more source

Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery

Advanced Science, EarlyView.
Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou, Xin‐Ge Wang, Xuan‐Ren Shi, Shu‐Ting Sun, Jing Mi, Xiao‐Peng Zhang, Bin‐Cheng Yin, Ying Zhou, Bang‐Ce Ye   +8 more
wiley   +1 more source

PREVALANCE OF SALMONELLA TYPHI CARRIER STATE PATIENTS WITH GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY [PDF]

Basrah Journal of Veterinary Research, 2005
A case control study was conducted in Busrah at the period from March to September 2002 . The population included in this study was divided into two groups .
Rahman K.Mohsen
doaj   +1 more source

AMPK and mTOR: sensors and regulators of immunometabolic changes during Salmonella infection in the chicken.

Poultry Science, 2016
Non-typhoidal Salmonella enterica induce an early pro-inflammatory response in chickens, but the response is short-lived, asymptomatic of clinical disease, results in a persistent colonization of the gastrointestinal (GI) tract, and can transmit ...
M. Kogut, K. Genovese, Haiqi He, R. Arsenault   +3 more
semanticscholar   +1 more source