Results 61 to 70 of about 125,644 (316)

Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis

Hepatology, EarlyView., 2022
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu, Xiude Fan, Megan R. McMullen, Tatsunori Miyata, Adam Kim, Vai Pathak, Jianguo Wu, Le Z. Day, Josiah E. Hardesty, Nicole Welch, Jaividhya Dasarathy, Daniela S. Allende, Arthur J. McCullough, Jon M. Jacobs, Daniel M. Rotroff, Srinivasan Dasarathy, Laura E. Nagy   +16 more
wiley   +1 more source

Sacroiliitis caused by Salmonella typhi

Journal of Infection in Developing Countries, 2009
Although the commonest manifestation of Salmonella infection is acute gastroenteritis, infection may spread to the blood-stream may and the illness can present with focal lesions in almost any organ with or without septicemia.
Mehmet Ulug, Mustafa Kemal Celen, Mehmet Faruk Geyik, Salih Hosoglu, Celal Ayaz   +4 more
doaj   +1 more source

Hydrogel‐Transformable Probiotic Powder for Targeted Eradication of Helicobacter pylori with Enhanced Gastric Mucosal Repair and Microbiota Preservation

Advanced Science, EarlyView.
A multifunctional, edible, and hydrogel‐transformable probiotic powder is developed based on the “bacteria‐mediated bacterial eradication” strategy. By leveraging the targeted binding capability of L. reuteri to H. pylori, this approach achieves an integrated therapeutic effect, including bactericidality, anti‐inflammation, gastric mucosal repair, and ...
Yongkang Lai, Hanchun Shen, Shige Wang, Yongliang Ouyang, Xinyuan Zhang, Bin Hu, Xiaoyi Zhang, Guisheng Li, Lizhi Xu, Jiulong Zhao   +9 more
wiley   +1 more source

Ice cream safety in the Dubrovnik area in the period 2006-2008

Mljekarstvo, 2010
From the epidemiological point of view, ice cream is a very risky foodstuff, which is illustrated by the fact that in 2006, 18.6% (520/2796) of samples from the entire Croatian market were microbiologically unsafe and, therefore, not in compliance with ...
Jakov Zadre, Aleksandar Racz, Lana Feher Turković   +2 more
doaj  

An Extreme Value Theory approach for the early detection of time clusters with application to the surveillance of Salmonella [PDF]

arXiv, 2010
We propose a method to generate a warning system for the early detection of time clusters applied to public health surveillance data. This new method relies on the evaluation of a return period associated to any new count of a particular infection reported to a surveillance system. The method is applied to Salmonella surveillance in France and compared
arxiv  

Facilitating crRNA Design by Integrating DNA Interaction Features of CRISPR‐Cas12a System

Advanced Science, EarlyView.
This study introduces a novel approach combining molecular dynamics simulations and neural network modeling to predict the Cas12a trans‐cleavage activity. By integrating sequence and molecular interaction features, prediction accuracy is enhanced, and identify key features affecting Cas12a trans‐cleavage activity.
Zhihao Yao, Wanglu Li, Kaiyu He, Hongmei Wang, Yan Xu, Qun Wu, Liu Wang, Yao Nie   +7 more
wiley   +1 more source

Bacteriophages Synergize with the Gut Microbial Community To Combat Salmonella

mSystems, 2018
Salmonella infection is one of the main causes of food-borne diarrheal diseases worldwide. Although most Salmonella infections can be cleared without treatment, some cause serious illnesses that require antibiotic treatment.
Yue O. O. Hu, Luisa W. Hugerth, Carina Bengtsson, Arlisa Alisjahbana, Maike Seifert, Anaga Kamal, Åsa Sjöling, Tore Midtvedt, Elisabeth Norin, Juan Du, Lars Engstrand   +10 more
doaj   +3 more sources

A Smart Single‐Loop‐Mediated Isothermal Amplification Facilitates Flexible SNP Probe Design for On‐Site Rapid Differentiation of SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
The ssLAMP method amplifies the nucleic acid of pathogen and identifies SNP mutations. By combining the portable detection device with smartphone‐based analysis software, enables rapid, on‐site SNP detection and genotyping of SARS‐Cov‐2 Omicron variants, providing a cost‐effective and field‐deployable solution for precise pathogen identification in ...
Qijie Lin, Hongchao Gou, Xiaoyun Qu, Kaiyuan Jia, Yuhui Deng, Dan Li, Qianyi Cai, Yucen Liang, Xiaozhen Xu, Yanbin Li, Jianhan Lin, Letian Li, Yuhang Jiang, Shouwen Du, Lingcong Deng, Bailing Yan, Ruidong Liu, Chang Li, Jianmin Zhang, Ming Liao   +19 more
wiley   +1 more source

Molecular techniques to characterize the invA genes of Salmonella spp. for pathogen inactivation study in composting [PDF]

arXiv, 2014
The relatively low concentration of pathogen indicators, such Salmonella, in composting sometimes causes a problem with detection when using the conventional techniques. The presence of viable but non-culturable (VBNC) organisms is also a potential problem with Salmonella detection when using conventional techniques.
arxiv  

IID Sampling from Intractable Distributions [PDF]

arXiv, 2021
We propose a novel methodology for drawing iid realizations from any target distribution on the Euclidean space with arbitrary dimension. No assumption of compact support is necessary for the validity of our theory and method. Our idea is to construct an appropriate infinite sequence of concentric closed ellipsoids, represent the target distribution as
arxiv