Results 81 to 90 of about 3,500,060 (237)

Genome-wide whole blood microRNAome and transcriptome analyses reveal miRNA-mRNA regulated host response to foodborne pathogen Salmonella infection in swine

Scientific Reports, 2015
To understand the role of miRNAs in regulating genes involved in host response to bacterial infection and shedding of foodborne pathogens, a systematic profiling of miRNAs and mRNAs from the whole blood of pigs upon Salmonella challenge was performed.
Hua Bao, A. Kommadath, G. Liang, Xu Sun, Adriano S. Arantes, C. Tuggle, S. Bearson, G. Plastow, P. Stothard, L. Guan   +9 more
semanticscholar   +1 more source

Role of Inflammasomes in Salmonella Infection [PDF]

Frontiers in Microbiology, 2011
Pattern recognition receptors (PRRs) play a crucial role in both the detection of pathogens and the activation of the innate immune system. Nod-like receptors (NLR) family members are cytosolic PRRs that sense bacterial products or endogenous danger signals.
openaire   +3 more sources

Effect of Salmonella infection on cecal tonsil regulatory T cell properties in chickens.

Poultry Science, 2015
Two studies were conducted to study regulatory T cell [Treg (CD4⁺CD25⁺)] properties during the establishment of a persistent intestinal infection in broiler chickens.
R. Shanmugasundaram, M. Kogut, R. Arsenault, C. Swaggerty, K. Cole, J. M. Reddish, R. Selvaraj   +6 more
semanticscholar   +1 more source

Macrophages target Salmonella by Lc3-associated phagocytosis in a systemic infection model

Autophagy, 2019
Innate immune defense against intracellular pathogens, like Salmonella, relies heavily on the autophagy machinery of the host. This response is studied intensively in epithelial cells, the target of Salmonella during gastrointestinal infections. However,
S. Masud, Tomasz K. Prajsnar, V. Torraca, G. Lamers, Marianne Benning, Michiel van der Vaart, A. Meijer   +6 more
semanticscholar   +1 more source

Early Salmonella Typhimurium infection in pigs disrupts Microbiome composition and functionality principally at the ileum mucosa

Scientific Reports, 2018
Salmonella is a major foodborne pathogen which successfully infects animal species for human consumption such as swine. The pathogen has a battery of virulence factors which it uses to colonise and persist within the host.
H. Argüello, J. Estellé, S. Zaldívar-López, Á. Jiménez-Marín, A. Carvajal, M. A. López-Bascón, F. Crispie, O. O’Sullivan, P. Cotter, F. Priego-Capote, L. Morera, J. Garrido   +11 more
semanticscholar   +1 more source

Temporal and Anatomical Host Resistance to Chronic Salmonella Infection Is Quantitatively Dictated by Nramp1 and Influenced by Host Genetic Background

PLoS ONE, 2014
The lysosomal membrane transporter, Nramp1, plays a key role in innate immunity and resistance to infection with intracellular pathogens such as non-typhoidal Salmonella (NTS). NTS-susceptible C57BL/6 (B6) mice, which express the mutant Nramp1D169 allele,
W. P. Loomis, Matthew L. Johnson, Alicia Brasfield, Marie-Pierre Blanc, Jaehun Yi, Samuel I. Miller, B. Cookson, A. Hajjar   +7 more
semanticscholar   +1 more source

Independent bottlenecks characterize colonization of systemic compartments and gut lymphoid tissue by salmonella.

PLoS Pathogens, 2014
Vaccination represents an important instrument to control typhoid fever in humans and protects mice from lethal infection with mouse pathogenic serovars of Salmonella species.
Chee Han Lim, Sabrina Voedisch, Benjamin Wahl, Syed Fazle Rouf, Robert Geffers, Mikael Rhen, Oliver Pabst   +6 more
doaj   +1 more source

Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection

Nature Communications, 2018
Non-typhoidal Salmonella strains are responsible for invasive infections associated with high mortality and recurrence in sub-Saharan Africa, and there is strong evidence for clonal relapse following antibiotic treatment.
J. Rycroft, Bridget Gollan, G. Grabe, Alexander M. J. Hall, Angela M. Cheverton, G. Larrouy-Maumus, S. Hare, S. Helaine   +7 more
semanticscholar   +1 more source

Meta-analysis of Chicken – Salmonella infection experiments

BMC Genomics, 2012
Background Chicken meat and eggs can be a source of human zoonotic pathogens, especially Salmonella species. These food items contain a potential hazard for humans.
te Pas Marinus FW, Hulsegge Ina, Schokker Dirkjan, Smits Mari A, Fife Mark, Zoorob Rima, Endale Marie-Laure, Rebel Johanna MJ   +7 more
doaj   +1 more source

Malaria Parasite Infection Compromises Control of Concurrent Systemic Non-typhoidal Salmonella Infection via IL-10-Mediated Alteration of Myeloid Cell Function

PLoS Pathogens, 2014
Non-typhoidal Salmonella serotypes (NTS) cause a self-limited gastroenteritis in immunocompetent individuals, while children with severe Plasmodium falciparum malaria can develop a life-threatening disseminated infection.
Kristen L Lokken, Jason P Mooney, B. P. Butler, M. Xavier, J. Chau, Nicola Schaltenberg, R. Begum, Werner Müller, S. Luckhart, R. Tsolis   +9 more
semanticscholar   +1 more source