The Dual Role of the Gut Microbiota in Cancer Chemoresistance
Comparison between Microbiota and Cancer therapy. ABSTRACT Chemoresistance is one of the primary reasons that cancer chemotherapy fails to deliver successful treatment outcomes and contributes to poor overall survival rates for patients with cancer. New research has begun to shed light on the effects of the gut microbiome (GM).
Hamed Tahmasebi +3 more
wiley +1 more source
An Overview of Mobile Colistin Resistance (mcr) Genes in Gram-Negative Bacilli. [PDF]
Yadav MV, Pawar S, Patil S.
europepmc +1 more source
De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence
Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi +2 more
wiley +1 more source
Evaluation of the role of house lizards (Hemidactylus frenatus) in transmitting parasitic and bacterial pathogens to humans in Hajjah Governorate, Yemen. [PDF]
Mogalli NM.
europepmc +1 more source
Environmental and anthropogenic drivers of antibiotic resistance dissemination. The cycle reinforces how anthropogenic inputs, such as sewage, animal dung, hospital effluent, and agricultural runoff bring resistant bacteria and antibiotic residues into soil and water.
Punam Chowdhury +3 more
wiley +1 more source
Antimicrobial resistance patterns of Salmonella spp. identified from retail pork and raw side salads from Busia County, Kenya. [PDF]
Mbabu CM +6 more
europepmc +1 more source
Metabolic Regulation of Macrophages in Health and Disease
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang +6 more
wiley +1 more source
Visual and microscopic lesions of enteritis in slaughtered swine: pathogen identification and antimicrobial resistance implications. [PDF]
Neis LZ +4 more
europepmc +1 more source
Macrophage: Biological Functions, Diseases, and Therapeutic Targets
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun +4 more
wiley +1 more source
Protective Effect of <i>Escherichia coli Nissle 1917</i> on <i>Salmonella typhimurium</i> Infection by Regulating Intestinal Flora. [PDF]
Li ZJ +18 more
europepmc +1 more source

